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窄谱中波紫外线光疗治疗银屑病继发的假性卟啉症

Pseudoporphyria secondary to narrowband UVB phototherapy for psoriasis.

作者信息

Oh Carol, Jones Brad, Solomon Rustum, Egan Conleth A

机构信息

Department of Dermatology, Our Lady of Lourdes Hospital, Drogheda, Ireland.

出版信息

Australas J Dermatol. 2006 May;47(2):134-6. doi: 10.1111/j.1440-0960.2006.00249.x.

DOI:10.1111/j.1440-0960.2006.00249.x
PMID:16637812
Abstract

A 59-year-old woman undergoing narrowband UVB phototherapy for treatment of psoriasis presented suddenly with tense blisters on both hips. The blisters were asymptomatic and disappeared within 24 hours. Histopathology together with a negative porphyrin screen made the diagnosis of pseudoporphyria. Blood tests including a full blood count, urea and electrolytes, liver function tests and antinuclear autoantibodies were normal. The patient was otherwise healthy; there was no history of extensive sun exposure, sunbeds or medication with non-steroidal anti-inflammatory drugs. This presentation of pseudoporphyria secondary to narrowband UVB radiation is unusual, as UVB radiation is not known to be associated with pseudoporphyria.

摘要

一名59岁的女性因银屑病接受窄谱中波紫外线(UVB)光疗,突然双侧臀部出现紧张性水疱。这些水疱无症状,24小时内消失。组织病理学检查及卟啉筛查阴性,诊断为假性卟啉病。血常规、尿素和电解质、肝功能检查及抗核自身抗体等血液检查均正常。该患者其他方面健康;无长时间日晒、使用日光浴床或服用非甾体抗炎药的病史。这种由窄谱UVB辐射继发的假性卟啉病表现不常见,因为UVB辐射与假性卟啉病并无关联。

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