Anavekar Namrata S, Nixon Rosemary
Occupational Dermatology Research and Education Centre, Skin and Cancer Foundation, Victoria, Australia.
Australas J Dermatol. 2006 May;47(2):143-4. doi: 10.1111/j.1440-0960.2006.00251.x.
A 46-year-old woman, who worked as a laminator of spa baths, presented with hand dermatitis, which was suspected to be related to her occupation. Patch testing revealed strong reactions to both cobalt chloride and a polyester resin that the patient had been using at her workplace. She also reacted to latex and had been wearing cotton gloves underneath rubber gloves at work. It was later discovered that cobalt octoate (synonym: cobalt-2-ethylhexanoate), a compound not listed on the manufacturer's material safety data sheet, was included as an accelerator in the polyester resin. She was then tested to cobalt octoate, which was also strongly positive. Her successful treatment included protection of her hands at work with cotton lined PVC gloves. This case highlights the role of cobalt salts as sensitizers and their presence as accelerators used in polyester resins, and the importance of recognizing concomitant latex allergy that may complicate occupational dermatitis. It also illustrates the difficulties in relying on material safety data sheets to identify all possible allergens.
一名46岁的女性,从事水疗浴缸贴膜工作,出现手部皮炎,怀疑与职业有关。斑贴试验显示,患者对氯化钴和她在工作场所使用的一种聚酯树脂均有强烈反应。她对乳胶也有反应,工作时一直在橡胶手套下面戴棉手套。后来发现,聚酯树脂中含有辛酸钴(同义词:2-乙基己酸钴)作为促进剂,而制造商的材料安全数据表上未列出该化合物。然后对她进行了辛酸钴测试,结果也呈强阳性。她成功的治疗方法包括在工作时使用内衬棉布的PVC手套保护双手。该病例突出了钴盐作为致敏剂的作用及其在聚酯树脂中作为促进剂的存在,以及认识到可能使职业性皮炎复杂化的乳胶过敏症的重要性。它还说明了依靠材料安全数据表来识别所有可能的过敏原存在困难。