Collins Michael J, Buehren Tobias, Bece Andrej, Voetz Stephanie C
Contact Lens and Visual Optics Laboratory, School of Optometry, Queensland University of Technology, Brisbane, Queensland, Australia.
Acta Ophthalmol Scand. 2006 Apr;84(2):216-24. doi: 10.1111/j.1600-0420.2005.00547.x.
To compare lid-induced changes in corneal optics following reading, microscopy and computer work.
Nine subjects with normal ocular health were recruited for the study. Five subjects were myopic, two were emmetropic, one was astigmatic and one was hyperopic. Corneal topography was measured before and after 60 mins of reading a novel, performing a blood cell counting task on a microscope and Internet searching. Corneal topography data were used to derive the corneal wavefront Zernike coefficients up to the fourth order. A meridian analysis of instantaneous corneal power along the upper 90-degree semi-meridian was performed to examine local changes caused by eyelid pressure. Digital photography was used to capture body posture and eyelid position during the tasks.
Each of the three tasks showed systematically different effects on both the characteristics and location of corneal topography changes. Reading and microscopy generally exhibited larger and more centrally located changes compared with the computer task. Differences in wavefront aberration characteristics between the three tasks were apparent in both lower and higher order aberrations. The location of corneal distortions differed significantly between microscopy and computer work, with microscopy causing distortions to occur closer to the videokeratoscope measurement axis compared with computer work (p = 0.015).
Reading, microscopy and computer work have different effects on corneal aberrations. The results are in agreement with the hypothesis that lid-induced corneal aberrations may play a role in myopia development.
比较阅读、显微镜操作和电脑工作后眼睑引起的角膜光学变化。
招募9名眼部健康正常的受试者进行研究。其中5名受试者为近视，2名受试者为正视，1名受试者为散光，1名受试者为远视。在阅读一本小说60分钟、在显微镜上进行血细胞计数任务以及进行互联网搜索前后测量角膜地形图。角膜地形图数据用于推导直至四阶的角膜波前泽尼克系数。沿上方90度半子午线对瞬时角膜屈光力进行子午线分析，以检查眼睑压力引起的局部变化。在任务过程中使用数码摄影捕捉身体姿势和眼睑位置。
三项任务中的每一项对角膜地形图变化的特征和位置均显示出系统性的不同影响。与电脑任务相比，阅读和显微镜操作通常表现出更大且更位于中心的变化。三项任务之间波前像差特征的差异在低阶和高阶像差中均很明显。显微镜操作和电脑工作之间角膜变形的位置存在显著差异，与电脑工作相比，显微镜操作导致的变形更靠近角膜地形图测量轴（p = 0.015）。
阅读、显微镜操作和电脑工作对角膜像差有不同影响。这些结果与眼睑引起的角膜像差可能在近视发展中起作用这一假设一致。
