Adami P, König P, Vetter Z, Hausmann A, Conca A
Department of Psychiatry I, Regional Hospital Rankweil, Rankweil, Austria.
Acta Psychiatr Scand. 2006 Apr;113(4):360-3; discussion 363-4. doi: 10.1111/j.1600-0447.2005.00737.x.
The case report suggests the indispensability of preoperative accurate psychiatric checkups especially in temporal resections.
A single case was reported.
We report the case of a 20-year-old woman suffering for 12 years from primary generalized epilepsy, attributed to left-sided hippocampal sclerosis. Because seizures were resistant to drug therapy, she underwent amygdala-hippocampectomy at the age of 18. Furthermore, she had previously been victim of childhood sexual abuse. Two weeks after epilepsy surgery, she manifested symptoms of post-traumatic stress disorder (PTSD).
There is evidence that the amygdala-hippocampal region is both functionally and morphologically involved in the aetiology of PTSD. The removal of this marked neuroanatomical region and the resulting disconnection and asymmetry between right and left amygdala-hippocampal region might be seen as an evidence for this region aetiologically being involved in the patient's PTSD symptoms.
该病例报告表明术前准确的精神科检查不可或缺，尤其是在颞叶切除术中。
报告了一例病例。
我们报告了一名20岁女性的病例，她患原发性全身性癫痫12年，病因是左侧海马硬化。由于癫痫发作对药物治疗耐药，她在18岁时接受了杏仁核-海马切除术。此外，她曾是童年性虐待的受害者。癫痫手术后两周，她出现了创伤后应激障碍（PTSD）的症状。
有证据表明杏仁核-海马区域在PTSD的病因学中在功能和形态上均有涉及。切除这一显著的神经解剖区域以及由此导致的左右杏仁核-海马区域之间的连接中断和不对称，可能被视为该区域在病因学上与患者PTSD症状有关的证据。
