Aghaei Shahin
Department of Dermatology, Jahrom Medical School, Jahrom, Iran.
Dermatol Online J. 2006 Feb 28;12(2):10.
This paper highlights the effect of diphenylcyclopropenone (DPCP) sensitization on warts resistant to other treatments and is interesting in views of the fact that all the facial warts apparently responded. To analyze the efficacy and side-effects of DPCP treatment of viral warts, a prospective study was designed to follow six patients with chronic and resistant facial warts through immunotherapy sensitization with diphenylcyclopropenone for 10 weekly sessions. Patients were first sensitized with 2 percent DPCP and then followed by weekly maintenance of 0.001-1 percent DPCP in acetone on facial warts until mild contact dermatitis was obtained. After application of DPCP to the warts of the face, all of the facial warts became inflamed and resolved. DPCP appears to be a valuable, safe, and well-tolerated treatment for resistant and chronic facial warts.
本文强调了二苯环丙烯酮（DPCP）致敏对其他治疗方法无效的疣的作用，鉴于所有面部疣显然都有反应，这一点很有趣。为了分析DPCP治疗病毒性疣的疗效和副作用，设计了一项前瞻性研究，对6例慢性且难治性面部疣患者进行免疫疗法致敏，每周使用二苯环丙烯酮，共10次。患者首先用2%的DPCP致敏，然后每周在面部疣上用0.001 - 1%的DPCP丙酮溶液维持治疗，直至出现轻度接触性皮炎。将DPCP应用于面部疣后，所有面部疣均出现炎症并消退。DPCP似乎是一种治疗难治性和慢性面部疣的有价值、安全且耐受性良好的治疗方法。
