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MicroMed DeBakey小儿心室辅助装置的初步经验。

Preliminary experience with the MicroMed DeBakey pediatric ventricular assist device.

作者信息

Fraser Charles D, Carberry Kathleen E, Owens W Richard, Arrington Karol A, Morales David L S, Heinle Jeffery S, McKenzie E Dean

机构信息

Michael E. DeBakey Department of Surgery, Division of Congenital Heart Surgery, Baylor College of Medicine, Houston, TX, USA.

出版信息

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006:109-14. doi: 10.1053/j.pcsu.2006.02.016.

DOI:10.1053/j.pcsu.2006.02.016
PMID:16638555
Abstract

Mechanical circulatory support for both acute and chronic heart failure is a widely applied therapeutic option in the adult population with a variety of devices clinically available. Technology in this field has advanced sufficiently such that long-term support or "destination therapy" has become a generally accepted reality. Similar progress has not occurred in the field of device support for heart failure in children. While the number of potential patients is significantly lower in the pediatric population, the clinical relevance and poignancy of individual need are nonetheless real. Until recently, children with heart failure have been largely disadvantaged in comparison to their adult counterparts. The DeBakey VAD Child (MicroMed Technology, Inc, Houston, TX) represents a hopeful initial step in the direction of reducing the technological gap between adults and children. While the clinical experience with this device is limited at present, preliminary results are encouraging. This report will provide an overview of the DeBakey VAD Child, including device specifications, indications for clinical use, surgical and postoperative considerations, and updated clinical experience.

摘要

对于急慢性心力衰竭,机械循环支持在成年人群中是一种广泛应用的治疗选择,临床上有多种可用设备。该领域的技术已经取得了足够的进展,以至于长期支持或“目标治疗”已成为普遍接受的现实。在儿童心力衰竭设备支持领域,类似的进展尚未出现。虽然儿科人群中潜在患者数量明显较少,但个体需求的临床相关性和紧迫性却是实实在在的。直到最近,与成年患者相比,心力衰竭儿童在很大程度上处于不利地位。德贝基儿童心室辅助装置(MicroMed Technology, Inc, 休斯顿,德克萨斯州)代表了在缩小成人和儿童技术差距方面充满希望的初步举措。虽然目前该设备的临床经验有限,但初步结果令人鼓舞。本报告将概述德贝基儿童心室辅助装置,包括设备规格、临床使用适应症、手术及术后注意事项以及最新的临床经验。

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Antithrombotic therapy in neonates and children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
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Chest. 2012 Feb;141(2 Suppl):e737S-e801S. doi: 10.1378/chest.11-2308.
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