Stasik Chad N, Giordano Thomas J, Gauger Paul G
University of Michigan Medical School, University of Michigan, Ann Arbor, MI 48109, USA.
Endocr Pract. 2005 Nov-Dec;11(6):382-4. doi: 10.4158/EP.11.6.382.
To report a case of ganglioneuroma masquerading as an incidental adrenal mass in an adult patient with Turner's syndrome.
We present the clinical, laboratory, radiologic, and pathologic findings in this patient.
A 31-year-old woman with Turner's syndrome who had previously been treated with growth hormone replacement had an incidentally discovered mass, apparently arising from the left adrenal gland. The mass was "silent" clinically and biochemically, but imaging characteristics were not reassuring for a benign cortical adenoma. Because of uncertainty regarding the nature of the mass, it was removed laparoscopically; during this procedure, it was noted to be intimately associated with, but anatomically distinct from, the left adrenal gland. The pathology report confirmed the presence of a benign ganglioneuroma.
Although ganglioneuroma has previously been noted to be associated with Turner's syndrome (especially in pediatric patients), to the best of our knowledge this is the first report of a ganglioneuroma manifesting as an incidental adrenal mass in an adult patient with Turner's syndrome.
报告一例在成年特纳综合征患者中伪装成偶然发现的肾上腺肿块的神经节瘤病例。
我们展示了该患者的临床、实验室、放射学和病理学检查结果。
一名31岁患有特纳综合征的女性，此前接受过生长激素替代治疗，偶然发现一个肿块，显然起源于左肾上腺。该肿块在临床和生化方面均“无异常表现”，但其影像学特征并不支持良性皮质腺瘤的诊断。由于肿块性质不确定，遂通过腹腔镜手术将其切除；在此过程中，发现它与左肾上腺紧密相连，但在解剖结构上与之不同。病理报告证实为良性神经节瘤。
尽管此前已注意到神经节瘤与特纳综合征有关（尤其是在儿科患者中），但据我们所知，这是首例在成年特纳综合征患者中表现为偶然发现的肾上腺肿块的神经节瘤报告。
