Sasaki Shugo, Yasuda Tetsuyuki, Kaneto Hideaki, Otsuki Michio, Tabuchi Yukiko, Fujita Yukari, Kubo Fumiyo, Tsuji Mayumi, Fujisawa Keiko, Kasami Ryuichi, Kitamura Tetsuhiro, Miyatsuka Takeshi, Katakami Naoto, Kawamori Dan, Matsuoka Taka-Aki, Imagawa Akihisa, Shimomura Iichiro
Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Japan.
Intern Med. 2012;51(17):2365-70. doi: 10.2169/internalmedicine.51.7726. Epub 2012 Sep 1.
We herein report the case of a 41-year-old male patient with an incidentally identified large adrenal ganglioneuroma (GN). His endocrine examinations were normal except for one episode of elevated urinary dopamine and noradrenaline levels. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) showed a large solid tumor with calcifications and a slightly lobular edge in the right adrenal gland. We performed open tumor excision and diagnosed it as adrenal ganglioneuroma. Adrenal GN is a rare benign tumor, and its hormonal activity and imaging characteristics are occasionally very similar to those of other adrenal tumors. Therefore, it needs careful evaluation by endocrine examinations and multiple imaging procedures to rule out other types of tumors.
我们在此报告一例41岁男性患者,偶然发现患有巨大肾上腺神经节细胞瘤(GN)。除了有一次尿多巴胺和去甲肾上腺素水平升高外,他的内分泌检查均正常。腹部计算机断层扫描(CT)和磁共振成像(MRI)显示右肾上腺有一个巨大的实性肿瘤,伴有钙化,边缘略呈分叶状。我们进行了开放性肿瘤切除术,诊断为肾上腺神经节细胞瘤。肾上腺GN是一种罕见的良性肿瘤,其激素活性和影像学特征偶尔与其他肾上腺肿瘤非常相似。因此,需要通过内分泌检查和多种影像学检查进行仔细评估,以排除其他类型的肿瘤。