Jakobi P, Krivoy N, Eibschitz I, Ziskind G
Department of Obstetrics/Gynecology B, Rambam Medical Center, Haifa, Israel.
Gynecol Obstet Invest. 1991;32(4):193-5. doi: 10.1159/000293029.
Plasma digoxin-like immunoreactive factor (DLIF) has been detected in various pathophysiological conditions associated with volume expansion. In this study, using radioimmunoassay, we confirmed the existence of high levels of DLIF in the stimulated follicular fluid, a rapidly volume-expanding biological model. The concentration of the various fractions of DLIF in follicular fluid was 2-9 times higher than in plasma, suggesting local concentration or production. No difference in concentration was observed between follicles containing fertilized oocytes and follicles with unfertilized oocytes. The role of DLIF in follicular homeostasis remains to be further investigated.
在与容量扩张相关的各种病理生理状况中已检测到血浆地高辛样免疫反应因子（DLIF）。在本研究中，我们使用放射免疫测定法，在快速容量扩张的生物学模型——刺激卵泡液中证实了高水平DLIF的存在。卵泡液中DLIF各组分的浓度比血浆中高2 - 9倍，提示存在局部浓缩或产生。在含有受精卵的卵泡和未受精卵的卵泡之间未观察到浓度差异。DLIF在卵泡内环境稳定中的作用仍有待进一步研究。
