Do Doan Hoa, Dalery Karl, Gervais André, Harvey Richard, Lepage Serge, Maltais Andrée, Nguyen Michel
Division of Cardiology, Centre Hospitalier Universitaire de Sherbrooke, Fleurimont, Québec, Canada.
Can J Cardiol. 2006 Apr;22(5):405-9. doi: 10.1016/s0828-282x(06)70926-6.
Recent evidence has shown the advantages of an early invasive strategy for patients with high-risk unstable angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI). However, the number of beds available for postangioplasty monitoring limits the use of this approach at the Centre hospitalier universitaire de Sherbrooke (Fleurimont, Quebec).
To study the safety of a protocol allowing the same-day return of patients with UA or NSTEMI to their referring hospital after angioplasty at the Centre hospitalier universitaire de Sherbrooke.
From June 2001 to June 2003, of the 532 patients with UA and NSTEMI who underwent percutaneous coronary intervention with planned same-day transfer back to their referring hospital, 419 consecutive patients who were eligible to return the same day were prospectively followed for 24 h.
Stents were used in 94.7% of patients and platelet glycoprotein IIb/IIIa receptor antagonists were used in 34.8% of patients. For 85% of patients, the femoral artery was used as the access route for percutaneous coronary intervention. The mean time that patients stayed in the hospital after angioplasty before returning to their referring centres was 4.4 h. No deaths, life-threatening arrhythmias or urgent revascularizations were reported during the 24 h postangioplasty follow-up period, but one patient had a major bleeding complication. During the study period, the mean angioplasty waiting time decreased from 5.7 days to 2.1 days.
The protocol evaluated in the present article is safe. It frees more beds, thus reducing the waiting list and allowing patients with high-risk acute coronary syndromes without ST segment elevation from community hospitals to benefit from the advantages of an early invasive strategy.
最近的证据表明,对于高危不稳定型心绞痛(UA)和非ST段抬高型心肌梗死(NSTEMI)患者,早期侵入性策略具有优势。然而,在舍布鲁克大学中心医院(魁北克省弗勒里蒙),血管成形术后监测可用床位数量限制了该方法的应用。
研究一项方案的安全性,该方案允许舍布鲁克大学中心医院血管成形术后的UA或NSTEMI患者当天返回其转诊医院。
2001年6月至2003年6月,532例接受经皮冠状动脉介入治疗并计划当天转回转诊医院的UA和NSTEMI患者中,对419例符合当天返回条件的连续患者进行了24小时前瞻性随访。
94.7%的患者使用了支架,其中34.8%的患者使用了血小板糖蛋白IIb/IIIa受体拮抗剂。85%的患者经股动脉途径进行经皮冠状动脉介入治疗。血管成形术后患者在返回转诊中心之前在医院的平均停留时间为4.4小时。血管成形术后24小时随访期间未报告死亡、危及生命的心律失常或紧急血管重建情况,但有1例患者发生了严重出血并发症。在研究期间,血管成形术的平均等待时间从5.7天降至2.1天。
本文评估的方案是安全的。它释放了更多床位,从而减少了等待名单,并使社区医院中无ST段抬高的高危急性冠状动脉综合征患者能够受益于早期侵入性策略的优势。