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门诊患者冠状动脉血管成形术的初步研究。

A pilot study of coronary angioplasty in outpatients.

作者信息

Laarman G J, Kiemeneij F, van der Wieken L R, Tijssen J G, Suwarganda J S, Slagboom T

机构信息

Amsterdam Department of Interventional Cardiology Onze Lieve Vrouwe Gasthuis, The Netherlands.

出版信息

Br Heart J. 1994 Jul;72(1):12-5. doi: 10.1136/hrt.72.1.12.

Abstract

BACKGROUND

Is it safe to discharge patients from hospital on the same day as percutaneous transluminal coronary angioplasty (PTCA)? The hypothesis tested was that careful pre and post angioplasty selection of patients can identify a group that is at very low risk of postprocedural complications and that these patients may be discharged on the day of the procedure.

METHODS

63 patients undergoing limited risk coronary angioplasty of 72 lesions were studied. So that patients would be able to walk soon after PTCA miniature equipment (6 French catheters and balloon-on-a-wire devices) was passed percutaneously through the right brachial artery. After coronary angioplasty patients with angiographic evidence of dissection and/or thrombus and with complications were assigned to an inpatient group and those in whom PTCA had achieved a good angiographic result were assigned to an outpatient group.

RESULTS

Two patients were excluded because the brachial approach failed, leaving 61 patients (70 lesions). After PTCA 50 patients (82%) with 57 lesions (81%) attempted were assigned to the outpatient group. No cardiac complication occurred in this subset (0%; 95% confidence interval 0 to 7%). Eleven patients (18%), in whom 13 lesions (19%) were attempted, were assigned to the inpatient group. Three of these patients (27%; 95% confidence interval 6 to 61%) had cardiac complications. Two patients needed local surgical repair after catheterisation of the brachial artery; one had a haematoma and one had a false aneurysm.

CONCLUSIONS

Coronary angioplasty with miniature equipment passed through the brachial artery was a safe procedure with a high initial success rate. The results of this pilot trial suggest that with careful selection of patients before and after angioplasty PTCA can be performed safely in outpatients.

摘要

背景

经皮腔内冠状动脉成形术(PTCA)当日出院的患者是否安全?所检验的假设是,在血管成形术前后仔细挑选患者,可以识别出术后并发症风险极低的一组患者,且这些患者可在手术当日出院。

方法

对63例接受72处病变有限风险冠状动脉成形术的患者进行研究。为使患者在PTCA后能尽快行走,将微型设备(6F导管和导丝球囊装置)经皮穿过右肱动脉。冠状动脉成形术后,有血管造影显示夹层和/或血栓及有并发症的患者被归入住院组,PTCA取得良好血管造影结果的患者被归入门诊组。

结果

2例患者因肱动脉入路失败被排除,剩余61例患者(70处病变)。PTCA后,50例患者(82%)的57处病变(81%)尝试被归入门诊组。该亚组未发生心脏并发症(0%;95%置信区间0至7%)。11例患者(18%)的13处病变(19%)尝试被归入住院组。其中3例患者(27%;95%置信区间6至61%)发生心脏并发症。2例患者在肱动脉插管后需要局部手术修复;1例有血肿,1例有假性动脉瘤。

结论

经肱动脉置入微型设备进行冠状动脉成形术是一种安全的手术,初始成功率高。该初步试验结果表明,通过血管成形术前后仔细挑选患者,PTCA可在门诊患者中安全进行。

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