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[终末期青光眼患者的白内障手术]

[Cataract surgery in patients with end-stage glaucoma].

作者信息

Altmeyer M, Wirbelauer C, Häberle H, Pham D T

机构信息

Klinik für Augenheilkunde, Vivantes Klinikum Neukölln, Berlin.

出版信息

Klin Monbl Augenheilkd. 2006 Apr;223(4):297-302. doi: 10.1055/s-2005-858720.

DOI:10.1055/s-2005-858720
PMID:16639667
Abstract

BACKGROUND

The purpose of this study was to assess the benefit of cataract surgery in patients with advanced cataract and glaucoma.

METHODS

In a prospective study, we investigated 12 consecutive patients (12 eyes). Inclusion criteria were the diagnosis of cataract and end-stage glaucoma with a cup-disc ratio (CD) of 0.9-1.0 and marked visual field defects with partially preserved central function. Preoperatively, at the third postoperative day and after 6 months (2-11 months), the visual acuity (V), the intraocular pressure (IOP), the number of antiglaucomatous drugs and the visual fields were assessed. Furthermore, the surgical procedure and possible complications were noted. In all patients cataract surgery was performed with topical anaesthesia.

RESULTS

10 patients were treated with cataract surgery alone, whereas 2 patients underwent combined cataract and glaucoma surgery. The mean visual acuity improved significantly from 0.3 to 0.5 (p = 0.007). Additionally a significant intraocular pressure reduction of 4.4 mm Hg (p = 0.007) was observed. The number of antiglaucomatous drugs decreased from 1.5 preoperatively to 0.8 postoperatively. The mean deviation (MD) improved from -27.5 dB up to -26.4 dB (p = 0.036) after 6 months.

CONCLUSION

Patients with progressive cataract and end-stage glaucoma can benefit from cataract surgery. Although marked visual field defects were present, an increase in visual acuity as well as a decrease of intraocular pressure may be achieved without worsening of the visual fields.

摘要

背景

本研究的目的是评估白内障手术对晚期白内障合并青光眼患者的益处。

方法

在一项前瞻性研究中,我们连续调查了12例患者(12只眼)。纳入标准为诊断为白内障和终末期青光眼,杯盘比(CD)为0.9 - 1.0,伴有明显视野缺损且部分中心功能保留。术前、术后第3天以及6个月(2 - 11个月)后,评估视力(V)、眼压(IOP)、抗青光眼药物数量和视野。此外,记录手术过程及可能的并发症。所有患者均采用表面麻醉进行白内障手术。

结果

10例患者仅接受白内障手术,而2例患者接受了白内障联合青光眼手术。平均视力从0.3显著提高至0.5(p = 0.007)。此外,观察到眼压显著降低4.4 mmHg(p = 0.007)。抗青光眼药物数量从术前的1.5种降至术后的0.8种。6个月后平均偏差(MD)从 - 27.5 dB改善至 - 26.4 dB(p = 0.036)。

结论

进行性白内障合并终末期青光眼患者可从白内障手术中获益。尽管存在明显的视野缺损,但在不使视野恶化的情况下,可实现视力提高以及眼压降低。

相似文献

1
[Cataract surgery in patients with end-stage glaucoma].[终末期青光眼患者的白内障手术]
Klin Monbl Augenheilkd. 2006 Apr;223(4):297-302. doi: 10.1055/s-2005-858720.
2
Risk of sudden visual loss following filtration surgery in end-stage glaucoma.晚期青光眼滤过手术后突然视力丧失的风险。
Am J Ophthalmol. 2005 Oct;140(4):661-6. doi: 10.1016/j.ajo.2005.04.016.
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[Cataract surgery in 79 patients with relative anterior microphthalmus (RAM): a review of anatomy, associated pathology and complications].[79例相对小眼球患者的白内障手术:解剖结构、相关病理学及并发症综述]
Klin Monbl Augenheilkd. 2000 Jun;216(6):369-76. doi: 10.1055/s-2000-10583.
4
[Effect of cataract surgery for visual field in glaucoma patients].[白内障手术对青光眼患者视野的影响]
Oftalmologia. 2007;51(2):73-80.
5
[Analysis of combined glaucoma and cataract operations with intraocular lens implantation: a study based on own material].
Klin Oczna. 2001;103(1):43-6.
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Seven-year follow-up of combined cataract extraction and viscocanalostomy.白内障摘除联合小梁切开术的七年随访
J Cataract Refract Surg. 2006 Dec;32(12):2043-9. doi: 10.1016/j.jcrs.2006.08.035.
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Phaco-trabeculotomy combined with deep sclerectomy, a new technique in combined cataract and glaucoma surgery: complication profile.超声乳化小梁切除术联合深层巩膜切除术,一种白内障与青光眼联合手术的新技术:并发症情况
Acta Ophthalmol Scand. 2007 Mar;85(2):143-8. doi: 10.1111/j.1600-0420.2006.00785.x.
8
Visual prognosis in advanced glaucoma: a comparison of medical and surgical therapy for retention of vision in 101 eyes with advanced glaucoma.晚期青光眼的视觉预后:101例晚期青光眼患者视力保留的药物治疗与手术治疗对比研究
Trans Am Ophthalmol Soc. 1977;75:539-55.
9
[Result of operations for hyper-mature cataract complicated with phacolytic glaucoma].[过熟期白内障合并晶状体溶解性青光眼的手术结果]
Klin Oczna. 2002;104(5-6):350-3.
10
[Cataract and combined cataract/glaucoma surgery as intraocular pressure-reducing procedure in eyes with relative anterior microphthalmos].[白内障及白内障合并青光眼手术作为相对性小眼球眼降低眼压的手术方法]
Klin Monbl Augenheilkd. 2005 Mar;222(3):206-10. doi: 10.1055/s-2005-858009.

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Estimating the rate of severe visual loss (wipe-out) following cataract surgery, a British Ophthalmological Surveillance Unit (BOSU) study.评估白内障手术后严重视力丧失(失明)的发生率,英国眼科监测单位(BOSU)研究。
Eye (Lond). 2023 Dec;37(18):3787-3792. doi: 10.1038/s41433-023-02606-9. Epub 2023 Jun 16.
2
The role of lens extraction in glaucoma management.晶状体摘除术在青光眼治疗中的作用。
Ann Transl Med. 2020 Nov;8(22):1550. doi: 10.21037/atm-20-3251a.
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Effect of intraocular lens implantation on visual field in glaucoma and comorbid cataracts.
人工晶状体植入对青光眼合并白内障患者视野的影响。
Int J Ophthalmol. 2020 Apr 18;13(4):580-586. doi: 10.18240/ijo.2020.04.08. eCollection 2020.