Altmeyer M, Wirbelauer C, Häberle H, Pham D T
Klinik für Augenheilkunde, Vivantes Klinikum Neukölln, Berlin.
Klin Monbl Augenheilkd. 2006 Apr;223(4):297-302. doi: 10.1055/s-2005-858720.
The purpose of this study was to assess the benefit of cataract surgery in patients with advanced cataract and glaucoma.
In a prospective study, we investigated 12 consecutive patients (12 eyes). Inclusion criteria were the diagnosis of cataract and end-stage glaucoma with a cup-disc ratio (CD) of 0.9-1.0 and marked visual field defects with partially preserved central function. Preoperatively, at the third postoperative day and after 6 months (2-11 months), the visual acuity (V), the intraocular pressure (IOP), the number of antiglaucomatous drugs and the visual fields were assessed. Furthermore, the surgical procedure and possible complications were noted. In all patients cataract surgery was performed with topical anaesthesia.
10 patients were treated with cataract surgery alone, whereas 2 patients underwent combined cataract and glaucoma surgery. The mean visual acuity improved significantly from 0.3 to 0.5 (p = 0.007). Additionally a significant intraocular pressure reduction of 4.4 mm Hg (p = 0.007) was observed. The number of antiglaucomatous drugs decreased from 1.5 preoperatively to 0.8 postoperatively. The mean deviation (MD) improved from -27.5 dB up to -26.4 dB (p = 0.036) after 6 months.
Patients with progressive cataract and end-stage glaucoma can benefit from cataract surgery. Although marked visual field defects were present, an increase in visual acuity as well as a decrease of intraocular pressure may be achieved without worsening of the visual fields.
本研究的目的是评估白内障手术对晚期白内障合并青光眼患者的益处。
在一项前瞻性研究中,我们连续调查了12例患者(12只眼)。纳入标准为诊断为白内障和终末期青光眼,杯盘比(CD)为0.9 - 1.0,伴有明显视野缺损且部分中心功能保留。术前、术后第3天以及6个月(2 - 11个月)后,评估视力(V)、眼压(IOP)、抗青光眼药物数量和视野。此外,记录手术过程及可能的并发症。所有患者均采用表面麻醉进行白内障手术。
10例患者仅接受白内障手术,而2例患者接受了白内障联合青光眼手术。平均视力从0.3显著提高至0.5(p = 0.007)。此外,观察到眼压显著降低4.4 mmHg(p = 0.007)。抗青光眼药物数量从术前的1.5种降至术后的0.8种。6个月后平均偏差(MD)从 - 27.5 dB改善至 - 26.4 dB(p = 0.036)。
进行性白内障合并终末期青光眼患者可从白内障手术中获益。尽管存在明显的视野缺损,但在不使视野恶化的情况下,可实现视力提高以及眼压降低。