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根尖周手术中两种引导组织再生技术对根尖边缘缺损的愈合反应:一项双盲随机临床试验。

Healing response of apicomarginal defects to two guided tissue regeneration techniques in periradicular surgery: a double-blind, randomized-clinical trial.

作者信息

Marín-Botero M L, Domínguez-Mejía J S, Arismendi-Echavarría J A, Mesa-Jaramillo A L, Flórez-Moreno G A, Tobón-Arroyave S I

机构信息

Grupo de Investigación en Patología Oral, Periodoncia y Cirugía Alvéolo-Dentaria, Laboratorio de Inmunodetección y Bioanálisis Facultad de Odontología, Universidad de Antioquia, Medellín, Colombia.

出版信息

Int Endod J. 2006 May;39(5):368-77. doi: 10.1111/j.1365-2591.2006.01081.x.

Abstract

AIM

To compare healing responses to periosteal sliding grafts and polyglactin 910 periodontal mesh used as guided tissue regeneration (GTR) materials/techniques when both periapical and periradicular bone loss are present.

METHODOLOGY

Thirty patients with suppurative chronic apical periodontitis with apicomarginal communication were selected and allocated randomly into two groups according to the barrier technique to be used during periradicular surgery: periosteal graft group (n = 15) and bioabsorbable membrane group (n = 15). Clinical and radiological evaluations were completed prior to surgery, a week later and every 3 months after surgery up to 12 months to measure the periodontal pocket depth (PD), clinical attachment level (CAL), gingival margin position (GMP), size of periapical lesion, percentage reduction of the periapical rarefaction, and periapical healing.

RESULTS

Both groups showed highly significant (P < 0.001) reductions in periodontal PD, CAL and size of periapical lesion at 12 months whilst GMP was unaltered. No significant difference between the experimental groups was evident for these parameters, or for the percentage reduction of size of the periapical lesion and clinical-radiographic healing.

CONCLUSION

Guided tissue regeneration applied to apicomarginal defects using sliding periosteal grafts and use of bioabsorbable membranes led to similar enhancements of the clinical outcome of periradicular surgery in terms of periapical healing, gain of periodontal support, PD reduction and minimal recession of the gingival margin.

摘要

目的

比较在根尖周和根周骨丧失均存在时,将骨膜滑动移植片和聚乙醇酸910牙周网用作引导组织再生(GTR)材料/技术的愈合反应。

方法

选择30例伴有根尖边缘交通的化脓性慢性根尖周炎患者,根据根周手术中使用的屏障技术随机分为两组:骨膜移植组(n = 15)和生物可吸收膜组(n = 15)。在手术前、术后1周以及术后每3个月直至12个月完成临床和影像学评估,以测量牙周袋深度(PD)、临床附着水平(CAL)、牙龈边缘位置(GMP)、根尖周病变大小、根尖周稀疏区缩小百分比以及根尖周愈合情况。

结果

两组在12个月时牙周PD、CAL和根尖周病变大小均有极显著(P < 0.001)降低,而GMP未改变。这些参数在实验组之间无显著差异,根尖周病变大小缩小百分比和临床 - 影像学愈合情况也无显著差异。

结论

在根尖边缘缺损处应用骨膜滑动移植片和生物可吸收膜进行引导组织再生,在根尖周愈合、牙周支持增加、PD降低以及牙龈边缘最小退缩方面,导致根周手术的临床结果有相似的改善。

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