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阿替卡因:一种用于肌肉筋膜深度无痛手术的有效辅助局部麻醉剂。

Articaine: an effective adjunctive local anesthetic for painless surgery at the depth of the muscular fascia.

作者信息

Schulze Keith E, Cohen Philip R, Nelson Bruce R

机构信息

Dermatologic Surgery Center of Houston, P.A., and University of Texas, Houston Medical School 77030, USA.

出版信息

Dermatol Surg. 2006 Mar;32(3):407-10. doi: 10.1111/j.1524-4725.2006.032082.x.

Abstract

BACKGROUND

Articaine is a unique amide anesthetic that contains a thiophene ring and an additional ester group. The rapid diffusion and enhanced tissue-penetrating properties of articaine enable its use for infiltrative anesthesia.

OBJECTIVE

To describe the effective use of articaine as an adjuvant local anesthetic for surgical excisions requiring dissection at the level of the muscular fascia.

METHODS AND MATERIALS

We discuss the successful adjunctive use of articaine to provide effective infiltrative anesthesia of muscular fascia. We review the composition, the pharmacologic properties, and the safety profile of articaine.

RESULTS

Adjuvant local anesthesia using articaine results in painless surgery at the level of the muscular fascia without any perioperative complications.

CONCLUSION

Articaine is not only well tolerated but also rapidly effective for anesthesia in the fascial plane of the trunk and extremities. We recommend it be considered as an adjunctive local anesthetic for consistently painless cutaneous surgery near the muscular fascia.

摘要

背景

阿替卡因是一种独特的酰胺类局部麻醉药,含有噻吩环和一个额外的酯基。阿替卡因的快速扩散和增强的组织穿透特性使其可用于浸润麻醉。

目的

描述阿替卡因作为辅助局部麻醉药在需要在肌筋膜水平进行解剖的手术切除中的有效应用。

方法和材料

我们讨论了阿替卡因成功辅助用于提供有效的肌筋膜浸润麻醉。我们回顾了阿替卡因的成分、药理特性和安全性。

结果

使用阿替卡因进行辅助局部麻醉可在肌筋膜水平实现无痛手术,且无任何围手术期并发症。

结论

阿替卡因不仅耐受性良好,而且在躯干和四肢的筋膜平面麻醉中起效迅速。我们建议将其视为在肌筋膜附近进行持续无痛皮肤手术的辅助局部麻醉药。

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