[卵巢癌术后加速康复方案]
[Accelerated course after operation for ovarian cancer].
作者信息
Marx Charlotte Iben, Rasmussen Tina, Jakobsen Dorthe Hjort, Ottosen Christian, Lundvall Lene, Ottesen Bent S, Callesen Torben, Kehlet Henrik
机构信息
H:S Rigshospitalet, Juliane Marie Centret, Gynaekologisk Klinik, Enhed for Kirurgisk Patofysiologi og Anaestesiafdelingen, København Ø.
出版信息
Ugeskr Laeger. 2006 Apr 10;168(15):1533-6.
INTRODUCTION
Introduction of principles for postoperative multimodal rehabilitation (fast track surgery) has decreased hospital stay from about 8-10 days to 2-4 days after colonic resection. The aim of this study was to investigate the effect of a similar fast track regimen in patients operated for ovarian cancer.
METHOD
72 consecutive patients operated with a conventional perioperative treatment regimen (group 1) were compared with the initial 69 consecutive patients (group 2) with a multimodal rehabilitation regimen and the next 50 consecutive patients (group 3) where the fast track regimen was implemented as a routine.
RESULTS
Patients demographics and surgical characteristics were comparable between groups. Median postoperative hospital stay was reduced from six days in group 1, to five days in group 2, and four days in group 3 (p < 0,05). Surgical complications were similar while medical complications were reduced from 12% to 1% (p < 0,05) and readmissions from 10% to 2% (p < 0,05) with the fast track regimen.
CONCLUSION
Principles for postoperative multimodal rehabilitation from colonic surgery lead to faster rehabilitation, decreased risk of medical complications and hospital stay in patients operated for ovarian cancer.
引言
术后多模式康复（快速康复外科）原则的引入已使结肠切除术后的住院时间从约8 - 10天缩短至2 - 4天。本研究的目的是调查类似的快速康复方案对卵巢癌手术患者的影响。
方法
将72例采用传统围手术期治疗方案的连续手术患者（第1组）与最初69例采用多模式康复方案的连续患者（第2组）以及接下来50例将快速康复方案作为常规实施的连续患者（第3组）进行比较。
结果
各组患者的人口统计学和手术特征具有可比性。术后中位住院时间从第1组的6天减少到第2组的5天，第3组为4天（p < 0.05）。手术并发症相似，而快速康复方案使医疗并发症从12%降至1%（p < 0.05），再入院率从10%降至2%（p < 0.05）。
结论
结肠手术术后多模式康复原则可使卵巢癌手术患者康复更快，降低医疗并发症风险并缩短住院时间。
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