Chudalla R, Baerwalde S, Schneider G, Maassen N
Sports and Exercise Physiology, Medical School Hannover, Carl-Neubergstrasse 1, 30625 Hannover, Germany.
Pflugers Arch. 2006 Sep;452(6):690-7. doi: 10.1007/s00424-006-0082-5. Epub 2006 Apr 27.
To evaluate the relationship between lactate release and lac and to investigate the influence of the catecholamines on the lactate release, 14 healthy men [age 25+/-3 (SE) year] were studied by superimposing cycle on forearm exercise, both at 65% of their maximal power reached in respective incremental tests. Handgrip exercise was performed for 30 min at 65% of peak power. In addition, between the tenth and the 22nd minute, cycling with the same intensity was superimposed. The increase in venous lactate concentration (lac) (rest: 1.3+/-0.4 mmol.l(-1); 3rd min: 3.9+/-0.8 mmol.l(-1)) begins with the forearm exercise, whereas arterial lactate concentration (lac) remains almost unchanged. Once cycling has been added to forearm exercise (COMB), lac increases with a concomitant increase in lac (12th min: lac, 3.2+/-1.3 mmol.l(-1); lac, 5.7+/-2.2 mmol.l(-1)). A correlation between oxygen tension (P(v)O(2)) and lac cannot be detected. There is a significant correlation between lac and norepinephrine ([NE]) (y=0.25x+1.2; r=0.815; p<0.01) but no correlation between lactate release and epinephrine ([EPI]) at moderate intensity. Our main conclusion is that lactate release from exercising muscles at moderate intensities is neither dependent on P(v)O(2) nor on [EPI] in the blood.
为了评估乳酸释放与动脉血乳酸浓度（lac）之间的关系，并研究儿茶酚胺对乳酸释放的影响，我们对14名健康男性[年龄25±3（标准误）岁]进行了研究，方法是在前臂运动的基础上叠加骑行运动，两者强度均为各自递增测试中达到的最大功率的65%。以最大功率的65%进行握力运动30分钟。此外，在第10至22分钟之间，叠加相同强度的骑行运动。静脉血乳酸浓度（lac）升高（静息时：1.3±0.4 mmol·l⁻¹；第3分钟：3.9±0.8 mmol·l⁻¹）始于前臂运动，而动脉血乳酸浓度（lac）几乎保持不变。一旦在前臂运动（COMB）中加入骑行运动，lac升高，同时lac也升高（第12分钟：lac，3.2±1.3 mmol·l⁻¹；lac，5.7±2.2 mmol·l⁻¹）。未检测到氧分压（P(v)O₂）与lac之间存在相关性。在中等强度下，lac与去甲肾上腺素（[NE]）之间存在显著相关性（y = 0.25x + 1.2；r = 0.815；p < 0.01），但乳酸释放与肾上腺素（[EPI]）之间无相关性。我们的主要结论是，中等强度运动时肌肉释放乳酸既不依赖于P(v)O₂，也不依赖于血液中的[EPI]。
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