Benarroch Fortu, Warman Orly, Gross-Tsur Varda
Hadassah University Hospital, Jerusalem.
Harefuah. 2006 Apr;145(4):292-7, 317.
Tourette Syndrome (TS) is a chronic, familial disorder, characterized by involuntary motor and phonic tics that wax and wane in severity. TS is frequently accompanied by behavioral, emotional and cognitive problems that are often more incapacitating than the tic disorder itself. After a review of the disorder, in which the multidisciplinary aspects are emphasized, the article describes the clinical features of 60 children with TS, 49 boys and 11 girls, aged 13 +/- 3.6 years (mean SD), treated in the Neuropediatric Unit at Shaare Zedek Medical Center. The children described had both motor and vocal tics, but also had ADHD (n = 44), obsessive-compulsive disorder (n = 32), learning disabilities (with 12 children learning in special education frameworks) and behavioral disorders (n = 36). The clinical profile of this group of children with TS is similar to that reported on referred patients regardless of cultural background. Since children with TS manifest multiple comorbidities, optimal therapy mandates the cooperation of a multidisciplinary team including a pediatric neurologist, a child psychiatrist, a psychologist and a family therapist. Working in concert, these specialists can implement a multimodal approach, addressing the neurological and psychiatric aspects of TS as well as enhancing the child's coping skills with the disorder itself and its consequences.
抽动秽语综合征(TS)是一种慢性的家族性疾病,其特征为不自主的运动性和发声性抽动,严重程度呈波动性变化。TS常伴有行为、情绪和认知问题,这些问题往往比抽动障碍本身更具致残性。在对该疾病进行综述(其中强调了多学科方面)之后,本文描述了在沙雷兹德克医学中心神经儿科接受治疗的60名TS患儿的临床特征,其中49名男孩,11名女孩,年龄为13±3.6岁(平均标准差)。所描述的这些患儿既有运动性抽动,也有发声性抽动,同时还患有注意力缺陷多动障碍(ADHD,n = 44)、强迫症(n = 32)、学习障碍(12名儿童在特殊教育框架下学习)以及行为障碍(n = 36)。无论文化背景如何,这组TS患儿的临床特征与转诊患者的报道相似。由于TS患儿表现出多种共病情况,最佳治疗需要多学科团队的合作,包括儿科神经科医生、儿童精神科医生、心理学家和家庭治疗师。这些专家协同工作,可以实施多模式方法,解决TS的神经学和精神学方面问题,同时提高患儿应对该疾病及其后果的技能。