Filippi M, Rocca M A, Arnold D L, Bakshi R, Barkhof F, De Stefano N, Fazekas F, Frohman E, Wolinsky J S
Neuroimaging Research Unit, Department of Neurology Scientific Institute and University Ospedale San Raffaele, Milan, Italy.
Eur J Neurol. 2006 Apr;13(4):313-25. doi: 10.1111/j.1468-1331.2006.01543.x.
Magnetic resonance (MR)-based techniques are widely used for the assessment of patients with suspected and definite multiple sclerosis (MS). However, despite the publication of several position papers, which attempted to define the utility of MR techniques in the management of MS, their application in everyday clinical practice is still suboptimal. This is probably related, not only, to the fact that the majority of published guidelines focused on the optimization of MR technology in clinical trials, but also to the continuing development of modern, quantitative MR-based techniques, that have not as yet entered the clinical arena. The present report summarizes the conclusions of the 'EFNS Expert Panel of Neuroimaging of MS' on the application of conventional and non-conventional MR techniques to the clinical management of patients with MS. These guidelines are intended to assist in the use of conventional MRI for the diagnosis and longitudinal monitoring of patients with MS. In addition, they should provide a foundation for the development of more widespread but rational clinical applications of non-conventional MR-based techniques in studies of MS patients.
基于磁共振(MR)的技术被广泛用于评估疑似和确诊的多发性硬化症(MS)患者。然而,尽管已发表了几篇立场文件,试图界定MR技术在MS管理中的效用,但它们在日常临床实践中的应用仍未达到最佳状态。这可能不仅与大多数已发表的指南侧重于临床试验中MR技术的优化有关,还与现代基于MR的定量技术的不断发展有关,这些技术尚未进入临床领域。本报告总结了“欧洲神经科学联合会MS神经影像学专家小组”关于常规和非常规MR技术在MS患者临床管理中的应用的结论。这些指南旨在协助使用传统MRI对MS患者进行诊断和纵向监测。此外,它们应为在MS患者研究中更广泛但合理地临床应用基于MR的非常规技术奠定基础。