2001年至2004年期间从希腊儿童中分离出的1033株肺炎球菌的血清型及抗菌药物敏感性
Serotypes and antimicrobial susceptibilities of 1033 pneumococci isolated from children in Greece during 2001-2004.
作者信息
Paraskakis I, Kafetzis D A, Chrisakis A, Papavasilliou H, Kirikou H, Pangalis A, Tzouvelekis L S, Athanasiou T, Legakis N J
机构信息
Clinical Microbiology Department of P. & A. Kyriakou (Annexe), Medical School, University of Athens, Aristofanous 56-58, Athens 152 32, Greece.
出版信息
Clin Microbiol Infect. 2006 May;12(5):490-3. doi: 10.1111/j.1469-0691.2006.01383.x.
Pneumococci (n = 1033) isolated in the major paediatric hospitals of Athens during 2001-2004 from children with invasive infections (n = 186), non-invasive infections (n = 641) and healthy carriers (n = 206) were studied. The most prevalent serotypes were serotypes 14 (44.6%), 19F (43.5%) and 6B (22.8%) in invasive, non-invasive and carriage isolates, respectively. Among invasive isolates, the potential coverage by the seven-valent conjugate vaccine was 75.3%. Resistance rates to penicillin, amoxycillin, cefotaxime, erythromycin, co-trimoxazole, clindamycin, tetracycline and chloramphenicol were 44.6%, 2.7%, 1.2%, 43.6%, 43.5%, 12.4%, 34.7% and 5.9%, respectively. The M-phenotype accounted for 68.0% of the erythromycin-resistant isolates. All isolates were susceptible to ofloxacin.
对2001年至2004年期间在雅典主要儿科医院从患有侵袭性感染（186例）、非侵袭性感染（641例）和健康携带者（206例）的儿童中分离出的肺炎球菌（n = 1033）进行了研究。侵袭性、非侵袭性和携带菌株中最常见的血清型分别为14型（44.6%）、19F型（43.5%）和6B型（22.8%）。在侵袭性菌株中，七价结合疫苗的潜在覆盖率为75.3%。对青霉素、阿莫西林、头孢噻肟、红霉素、复方新诺明、克林霉素、四环素和氯霉素的耐药率分别为44.
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