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STAN在临床实践中的应用——在哥德堡市两年常规使用的结果

STAN in clinical practice--the outcome of 2 years of regular use in the city of Gothenburg.

作者信息

Norén Håkan, Blad Sofia, Carlsson Ann, Flisberg Anders, Gustavsson Annika, Lilja Håkan, Wennergren Margareta, Hagberg Henrik

机构信息

Department of Obstetrics and Gynecology, Perinatal Center, Sahlgrenska University Hospital, Gothenburg, Sweden.

出版信息

Am J Obstet Gynecol. 2006 Jul;195(1):7-15. doi: 10.1016/j.ajog.2006.01.108. Epub 2006 Apr 27.

Abstract

OBJECTIVE

The purpose of this study was to monitor the introduction of the STAN-methodology (Noventa Medical, Moelndal, Sweden).

STUDY DESIGN

This was a prospective observational study covering the total population of deliveries at term during 2 years. Four thousand eight hundred and thirty out of 14,687 term pregnancies were monitored using the STAN S 21 fetal heart monitor and the associated clinical guidelines. Cord artery metabolic acidosis, neonatal outcome, and rates of operative deliveries for fetal distress were assessed.

RESULTS

The annual rate of STAN usage increased from 28.1% to 37.7% and was associated with a significant reduction in metabolic acidosis rate in the total population from 0.76% to 0.44% (P < .05). The compliance with the clinical guidelines increased in cases requiring intervention. The rates for moderate/severe hypoxic neonatal encephalopathy were consistently low, 0.55 and 0.68 per 1000 deliveries, respectively, and corresponding to previous findings. The rate of operative delivery did not change during the 2 years in the total population.

CONCLUSION

Increasing STAN usage provided consistent improvements in fetal outcome equalling those noted in the Swedish randomized controlled trial (RCT) without increasing operative interventions for fetal distress.

摘要

目的

本研究旨在监测STAN方法(瑞典莫恩达尔诺文塔医疗公司)的引入情况。

研究设计

这是一项前瞻性观察性研究,涵盖了两年内足月分娩的全部人群。在14,687例足月妊娠中,对4830例使用STAN S 21胎儿心脏监护仪及相关临床指南进行监测。评估脐动脉代谢性酸中毒、新生儿结局以及因胎儿窘迫而行手术分娩的发生率。

结果

STAN的年使用率从28.1%增至37.7%,且与总体人群中代谢性酸中毒发生率从0.76%显著降至0.44%相关(P <.05)。在需要干预的病例中,对临床指南的依从性有所提高。中度/重度缺氧性新生儿脑病的发生率一直较低,分别为每1000例分娩0.55例和0.68例,与先前的研究结果相符。总体人群中手术分娩率在两年间未发生变化。

结论

增加STAN的使用量可持续改善胎儿结局,与瑞典随机对照试验(RCT)中所观察到的效果相当,且不会增加因胎儿窘迫而进行的手术干预。

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