Gun'ko V M, Zarko V I, Voronin E F, Goncharuk E V, Andriyko L S, Guzenko N V, Nosach L V, Janusz W
Institute of Surface Chemistry, 17 General Naumov Street, 03164 Kiev, Ukraine.
J Colloid Interface Sci. 2006 Aug 1;300(1):20-32. doi: 10.1016/j.jcis.2006.03.034. Epub 2006 Apr 27.
Successive interaction of different pairs of water-soluble polymers (poly(ethylene glycol) (PEG), poly(vinyl pyrrolidone) (PVP), poly(vinyl alcohol) (PVA)), proteins (bovine serum albumin (BSA), ovalbumin, gelatin, and ossein), and smaller organics such as lecithin (1-stearoyl-2-oleoyl phosphatidylcholine, SOPC) and Aethonium (1,2-ethylene-bis(N-dimethyl carbodecyl oxymethyl) ammonium dichloride) with nanosilicas A-300 (S(BET)=232 and 297 m(2) g(-1)) and A-50 (S(BET)=52 m(2)g(-1)) was studied using dynamic light scattering, adsorption, and infrared (FTIR) spectroscopy methods. Time-dependent rearrangement of particle size distributions (PSDs) depicts appearance of both smaller and larger aggregates for silica/PEG(I-first adsorbate)/BSA(II-second adsorbate) and silica/PVP(I)/BSA(II) (i.e., BSA adsorbs onto PEG/silica or PVP/silica) than that for silica/organic compound I. However, in the cases of PVA(I)-BSA(II) and PVA(I)-SOPC(II) a similar effect is not observed because only increased aggregation occurs. The successive equilibrium adsorption of similar pairs shows a diminution of the adsorption of the second compound (gelatin, ovalbumin) with increasing amount of the first adsorbed polymer (PEG or PVP).
使用动态光散射、吸附和红外（FTIR）光谱法研究了不同水溶性聚合物对（聚乙二醇（PEG）、聚乙烯吡咯烷酮（PVP）、聚乙烯醇（PVA））、蛋白质（牛血清白蛋白（BSA）、卵清蛋白、明胶和骨胶原）以及较小的有机物如卵磷脂（1-硬脂酰-2-油酰磷脂酰胆碱，SOPC）和Aethonium（1,2-亚乙基-双（N-二甲基碳十二烷基氧甲基）氯化铵）与纳米二氧化硅A-300（S(BET)=232和297 m² g⁻¹）和A-50（S(BET)=52 m² g⁻¹）的连续相互作用。粒径分布（PSD）随时间的重排表明，与二氧化硅/有机化合物I相比，二氧化硅/PEG（I-第一种吸附物）/BSA（II-第二种吸附物）和二氧化硅/PVP（I）/BSA（II）（即BSA吸附到PEG/二氧化硅或PVP/二氧化硅上）会出现更小和更大的聚集体。然而，在PVA（I）-BSA（II）和PVA（I）-SOPC（II）的情况下，未观察到类似的效果，因为只发生了聚集增加。相似对的连续平衡吸附表明，随着第一种吸附聚合物（PEG或PVP）量的增加，第二种化合物（明胶、卵清蛋白）的吸附量会减少。
