来自苦西瓜的葫芦素糖苷。

Cucurbitacin glucosides from Citrullus colocynthis.

作者信息

Nayab Durey, Ali Dildar, Arshad Nuzhat, Malik Abdul, Choudhary M Iqbal, Ahmed Zaheer

机构信息

International Center for Chemical Sciences, HEJ, Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.

出版信息

Nat Prod Res. 2006 May 10;20(5):409-13. doi: 10.1080/14786410500044997.

DOI:10.1080/14786410500044997

PMID:16644537

Abstract

A new cucurbitacin glucoside 2-O-beta-D-glucopyranosyl-16alpha-20R-dihydroxy-cucurbita-1,5,23E,25(26)-tetraen-3,11,22-trione (1) has been isolated from the methanolic extract of the fruits of Citrulluscolocynthis. The structure has been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. In addition 2-O-beta-D-glucopyranosyl-cucurbitacin B (arvenin I) (2) and 2,25-di-O-beta-D-glucopyranosyl-cucurbitacin L (3) are reported for the first time from this species.

摘要

从苦西瓜果实的甲醇提取物中分离出一种新的葫芦素葡萄糖苷2-O-β-D-吡喃葡萄糖基-16α-20R-二羟基-葫芦巴-1,5,23E,25(26)-四烯-3,11,22-三酮(1)。其结构已通过包括一维和二维核磁共振技术在内的光谱分析确定。此外，首次从该物种中报道了2-O-β-D-吡喃葡萄糖基-葫芦素B(刺参素I)(2)和2,25-二-O-β-D-吡喃葡萄糖基-葫芦素L(3)。