Mihalek I, Res I, Lichtarge O
Department of Molecular and Human Genetics, Baylor College of Medicine One Baylor Plaza, Houston, TX 77030, USA. {imihalek,ires,lichtarge}@bcm.tmc.edu
Bioinformatics. 2006 Jul 1;22(13):1656-7. doi: 10.1093/bioinformatics/btl157. Epub 2006 Apr 27.
: Evolutionary trace report_maker offers a new type of service for researchers investigating the function of novel proteins. It pools, from different sources, information about protein sequence, structure and elementary annotation, and to that background superimposes inference about the evolutionary behavior of individual residues, using real-valued evolutionary trace method. As its only input it takes a Protein Data Bank identifier or UniProt accession number, and returns a human-readable document in PDF format, supplemented by the original data needed to reproduce the results quoted in the report.
进化追踪报告生成器为研究新型蛋白质功能的研究人员提供了一种新型服务。它从不同来源汇集有关蛋白质序列、结构和基本注释的信息,并在此背景上使用实值进化追踪方法叠加关于单个残基进化行为的推断。它仅以蛋白质数据库标识符或通用蛋白质资源库登录号作为输入,并返回一份PDF格式的、可供人类阅读的文档,同时还附带报告中引用结果所需的原始数据。