Corrado Domenico, Basso Cristina, Schiavon Maurizio, Thiene Gaetano
Department of Cardiology and Institute of Pathological Anatomy, University of Padova, Italy.
J Cardiovasc Med (Hagerstown). 2006 Apr;7(4):228-33. doi: 10.2459/01.JCM.0000219313.89633.45.
Vigorous physical exercise may precipitate acute fatalities in both adults and young competitive athletes with concealed heart diseases. However, the risk-benefit ratio of physical exercise differs among these two age groups. In adults, physical activity can be regarded as a 'double-edged sword': vigorous exertion increases the incidence of acute coronary events in individuals who did not exercise regularly, whereas habitual physical activity reduces the overall risk of myocardial infarction and sudden coronary death by preventing development and progression of atherosclerotic coronary artery disease. On the other hand, in adolescents and young adults sports activity is associated with a significant increase of the risk of sudden death. Sport is not per se the cause of the enhanced mortality in this age group; rather, it acts as a trigger of cardiac arrest in those athletes who are affected by silent cardiovascular conditions, mainly cardiomyopathy, premature coronary artery disease and congenital coronary anomalies, which predispose to life-threatening ventricular arrhythmias during physical exercise.
剧烈的体育锻炼可能会在患有隐匿性心脏病的成年人和年轻竞技运动员中引发急性死亡。然而,体育锻炼的风险效益比在这两个年龄组中有所不同。在成年人中,体育活动可被视为一把“双刃剑”:剧烈运动增加了不经常锻炼者急性冠状动脉事件的发生率,而习惯性体育活动则通过预防动脉粥样硬化性冠状动脉疾病的发展和进展,降低了心肌梗死和冠状动脉性猝死的总体风险。另一方面,在青少年和年轻人中,体育活动与猝死风险的显著增加有关。运动本身并非该年龄组死亡率增加的原因;相反,它是那些患有隐匿性心血管疾病(主要是心肌病、早发性冠状动脉疾病和先天性冠状动脉异常)的运动员心脏骤停的触发因素,这些疾病在体育锻炼期间易引发危及生命的室性心律失常。