Sison Margarette, Cawker Jacob, Buske Christine, Gerlai Robert
Department of Psychology, University of Toronto at Mississauga, 3359 Mississauga Rd., Mississauga, ON Canada.
Lab Anim (NY). 2006 May;35(5):33-9. doi: 10.1038/laban0506-33.
The zebrafish (Danio rerio) has been a favorite model of developmental biologists and geneticists, but only recently have investigators begun to appreciate its usefulness in behavior genetics. Papers focusing on the behavior or brain function of this species were once extremely rare, but during the past decade rapid growth has taken place. Despite the increased interest, however, the number of studies devoted to the analysis of the behavior of this species is still orders of magnitude less than those conducted on more traditional laboratory subjects including the rat and the mouse. The authors review selected literature and demonstrate that zebrafish is an excellent subject for behavior genetics research, especially in the area of forward genetics (mutagenesis).
斑马鱼（Danio rerio）一直是发育生物学家和遗传学家喜爱的模型，但直到最近研究人员才开始认识到它在行为遗传学中的有用性。专注于该物种行为或脑功能的论文曾经极为罕见，但在过去十年中数量迅速增长。然而，尽管关注度有所提高，但致力于分析该物种行为的研究数量仍比针对包括大鼠和小鼠在内的更传统实验室对象的研究数量少几个数量级。作者回顾了部分文献，并证明斑马鱼是行为遗传学研究的优秀对象，尤其是在前向遗传学（诱变）领域。
