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枕下开颅术后复发低级别星形细胞瘤手术通道内硬纤维瘤的发生与快速生长

Development and rapid growth of a desmoid tumor in the surgical corridor after suboccipital craniotomy for recurrent low-grade astrocytoma.

作者信息

McCall Todd, Rao Ganesh, Jensen Randy

机构信息

Department of Neurosurgery, University of Utah, Salt Lake City, Utah 84132, USA.

出版信息

J Neurooncol. 2006 Nov;80(2):167-70. doi: 10.1007/s11060-006-9166-5. Epub 2006 Apr 28.

DOI:10.1007/s11060-006-9166-5
PMID:16645711
Abstract

Desmoid tumors are histologically benign but locally invasive tumors that can occur in the head and neck. We present the rare case of a desmoid tumor that occurred in the surgical corridor after suboccipital craniotomy for recurrent low-grade astrocytoma. A 30-year-old woman underwent a repeat suboccipital craniotomy for recurrent low-grade astrocytoma. A gross total resection was achieved. Nine months later, a firm, palpable mass was noted near the surgical scar. No new neurologic deficits were noted on exam. A magnetic resonance imaging scan demonstrated a homogeneously enhancing lesion superficial to the dural graft. Surgical resection of the lesion was performed through the original midline incision. The mass was resected en bloc. Histology demonstrated clear surgical margins and a tumor of low cellularity consistent with a desmoid tumor. Desmoid tumors should be considered in the differential diagnosis for superficial masses occurring in the surgical bed after posterior cervical surgery.

摘要

硬纤维瘤是组织学上为良性但具有局部侵袭性的肿瘤,可发生于头颈部。我们报告了一例罕见的硬纤维瘤病例,该肿瘤发生在枕下开颅切除复发性低级别星形细胞瘤后的手术通道内。一名30岁女性因复发性低级别星形细胞瘤接受了再次枕下开颅手术。实现了肿瘤全切。九个月后,在手术瘢痕附近发现一个质地硬、可触及的肿块。检查未发现新的神经功能缺损。磁共振成像扫描显示在硬脑膜移植物表面有一个均匀强化的病变。通过原中线切口对病变进行了手术切除。肿块被整块切除。组织学检查显示手术切缘清晰,肿瘤细胞密度低,符合硬纤维瘤。对于颈椎后路手术后手术床出现的浅表肿块,鉴别诊断时应考虑硬纤维瘤。

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