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小脑成血管细胞瘤切除术后的硬纤维瘤

Desmoid tumor after resection of cerebellar hemangioblastoma.

作者信息

Rezaei Omidvar, Samadian Mohammad, Hosseinzadeh Bakhtevari Mehrdad, Darozarbi Amirarsalan A

机构信息

Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.

Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran -

出版信息

J Neurosurg Sci. 2019 Apr;63(2):224-230. doi: 10.23736/S0390-5616.16.03398-1.

Abstract

Desmoid tumors are histologically benign but locally invasive tumors that rarely can occur in the head and neck. In this article, we illustrate a rare case of desmoid tumor formation in intracranial posterior fossa after suboccipital craniotomy for hemangioblastoma. A 43-year-old woman presented with headaches, dizziness, equilibrium disorders, nausea, and vomiting due to a hemangioblastoma in posterior fossa. A gross total resection was achieved. Three years postoperatively, the patient developed a growing mass at the intracranial intradural regions in posterior fossa near the previous incision. Surgical resection of the lesion was performed and the mass was totally resected. Postoperative imaging demonstrated no residual evidence of tumor and the pathological review of the surgical tumor specimen demonstrated desmoid tumor in intracranial posterior fossa. As desmoid tumors seem to arise at the location of a previous surgical site, they should be considered in the differential diagnosis for superficial masses occurring in the surgical bed after posterior surgery. Additionally, identifying the relationship between the basic effects of tumor surgery and desmoid tumor formation is considerably needed.

摘要

硬纤维瘤是组织学上为良性但具有局部侵袭性的肿瘤,很少发生于头颈部。在本文中,我们阐述了1例在枕下开颅切除成血管细胞瘤后颅内后颅窝形成硬纤维瘤的罕见病例。一名43岁女性因后颅窝成血管细胞瘤出现头痛、头晕、平衡障碍、恶心和呕吐。实现了肿瘤全切。术后3年,患者在先前切口附近的后颅窝颅内硬膜内区域出现一个不断增大的肿块。对该病变进行了手术切除,肿块被完全切除。术后影像学检查未发现肿瘤残留证据,手术肿瘤标本的病理检查显示为颅内后颅窝硬纤维瘤。由于硬纤维瘤似乎出现在先前手术部位,对于后颅窝手术后手术床出现的浅表肿块进行鉴别诊断时应考虑到该病。此外,非常需要明确肿瘤手术的基本影响与硬纤维瘤形成之间的关系。

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