Labadze I Dzh, Gogoberidze M M, Khananashvili M M
IS Beritashvili Institute of Physiology, Georgian Academy of Sciences, Tbilisi.
Neurosci Behav Physiol. 2006 Jun;36(5):449-51. doi: 10.1007/s11055-006-0038-4.
An individual's zoosocial experience plays a significant role in the formation of adaptive behavior in animals. Published data show that significant restriction of intraspecies interactions induces impairments of higher nervous activity, including such functions as learning, memory, and the control of emotions. These changes are particularly marked when deprivation of zoosocial interactions occurs in the early stage of the animal's postnatal development. We have previously demonstrated that psychogenic stress in rats reared from an early age (from 14 days after birth) in conditions of visual and tactile deprivation leads to impairment of long-term (conditioned reflex) memory functions, this being accompanied by significant suppression of self-regulatory brain activity. The aim of the present work was to investigate the effects of partial intraspecies deprivation in early ontogenesis on overall behavior and short-term memory in adult rats.
个体的动物社交经历在动物适应性行为的形成中起着重要作用。已发表的数据表明，种内互动的显著受限会导致高级神经活动受损，包括学习、记忆和情绪控制等功能。当动物出生后发育早期出现动物社交互动剥夺时，这些变化尤为明显。我们之前已经证明，在视觉和触觉剥夺条件下从小（出生后14天起）饲养的大鼠中，心理应激会导致长期（条件反射）记忆功能受损，同时伴有自我调节脑活动的显著抑制。本研究的目的是探讨早期个体发育过程中部分种内剥夺对成年大鼠整体行为和短期记忆的影响。
