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[小儿麻痹后遗症患者肌肉运动单位的变化]

[Changes in the motor units of the muscles in patients with residual symptoms of poliomyelitis].

作者信息

Kasatkina L F

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(9):9-13.

PMID:1664625
Abstract

Based on an analysis of potentials of motor units (MU) of the skeletal muscles of patients with the postpoliomyelitis syndrome (PPMS), tick-borne encephalitis and spinal amyotrophy, a conclusion is made about the common trend of changes in MU in the given diseases. The degree of changes in MU depends on the grade of physical and trophic load of the preserved nerve elements. As the reserve possibilities of motoneurons are depleted, the process gets aggravated, with the formation of compensatory innervation insufficiency and the rise of muscle atrophy. In patients with PPMS, the decompensation of the pathological process starts, as a rule, at the definite age period and depends on the intensity of the primary defect formation.

摘要

基于对患有小儿麻痹后遗症(PPMS)、蜱传脑炎和脊髓性肌萎缩症患者骨骼肌运动单位(MU)电位的分析,得出了这些疾病中MU变化的共同趋势。MU的变化程度取决于保留的神经元件的物理和营养负荷等级。随着运动神经元储备能力的耗尽,病情会加重,形成代偿性神经支配不足并导致肌肉萎缩加剧。在PPMS患者中,病理过程的失代偿通常在特定年龄阶段开始,并取决于原发性缺陷形成的强度。

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