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在院前急救中治疗鹅膏蕈碱中毒的医疗差错。

Medical error in treatment of Amanita phalloides poisoning in pre-hospital care.

机构信息

Chair and Department of Forensic Medicine, Medical University of Lodz, ul. Sędziowska 18a, 91-304, Lodz, Poland.

Department of Emergency Medicine for Children, II Chair of Paediatrics, Medical University of Lodz, Lodz, Poland.

出版信息

Scand J Trauma Resusc Emerg Med. 2022 Mar 19;30(1):20. doi: 10.1186/s13049-022-01008-2.

Abstract

BACKGROUND

Geopolitical and climate changes form the background of the current migration crisis. It has many faces. One of them are the tragic cases of poisoning of refugees due to eating wild forest mushrooms for socioeconomic reasons in the Western and Northern European countries. The most serious food poisonings in Europe, but not only, are caused by lamellar mushrooms, the most dangerous being Amanita phalloides. Its poisonous properties can be attributed to α-amanitin, an RNA polymerase II inhibitor. Unfortunately, as it is characterized by a delayed onset of symptoms, A. phalloides poisoning has a high risk of complications.

CASE PRESENTATION

Our article presents a case of A. phalloides poisoning in a 28-year-old man, in which the responding medical emergency unit made errors in diagnosis and treatment. Since the correct diagnosis was made too late, the typical treatment of A. phalloides poisoning was ineffective. The patient suffered a life-threatening liver failure and needed liver transplant from a deceased donor.

CONCLUSIONS

Mushroom poisoning is a particularly important problem not only in countries with a mushroom picking tradition, but also-due to the inflow of refugees-in countries where mushroom poisoning was very rare until recently. In such cases it is crucial to quickly implement the correct procedure, as this can prevent the need for liver transplant or even death. This is a particularly important consideration for the first medical professionals to contact the patient, especially in cases where the patient reports mushrooms consumption and presents alarming symptoms of the gastrointestinal tract. Such situations cannot be underestimated and ignored.

摘要

背景

地缘政治和气候变化构成了当前移民危机的背景。它有许多表现形式。其中之一是由于经济社会原因,在西欧和北欧国家,难民食用野生森林蘑菇而中毒的悲惨案例。在欧洲,最严重的食物中毒事件(不仅限于欧洲)是由层状蘑菇引起的,其中最危险的是鹅膏菌。其毒性可归因于 RNA 聚合酶 II 抑制剂α-鹅膏蕈碱。不幸的是,由于其症状潜伏期长,鹅膏菌中毒有很高的并发症风险。

病例介绍

我们的文章介绍了一例 28 岁男性鹅膏菌中毒病例,其中响应的医疗急救单位在诊断和治疗方面犯了错误。由于诊断太迟,典型的鹅膏菌中毒治疗无效。患者发生危及生命的肝衰竭,需要从已故供体进行肝移植。

结论

蘑菇中毒不仅在有采蘑菇传统的国家是一个特别重要的问题,而且由于难民的涌入,在最近蘑菇中毒非常罕见的国家也是一个特别重要的问题。在这种情况下,快速实施正确的程序至关重要,因为这可以防止需要进行肝移植甚至死亡。对于首次接触患者的医疗专业人员来说,这是一个特别重要的考虑因素,尤其是在患者报告食用蘑菇并出现胃肠道警报症状的情况下。这种情况不容忽视。

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