Maillard C A, Edwards D A
Department of Psychology, Emory University, Atlanta, GA 30322.
Behav Brain Res. 1991 Dec 20;46(2):143-9. doi: 10.1016/s0166-4328(05)80107-x.
In male rats, ibotenic acid and N-methyl-D-aspartic acid were used to destroy neuronal perikarya intrinsic to an anterior-posterior continuum including the caudal zona incerta and lateral tegmentum. Some lesions virtually eliminated male sexual behavior - an effect most closely associated with damage to the lateral hypothalamus and zona incerta. Many lesioned males who copulated to ejaculation with normally active females showed little or no mating with receptive, but relatively inactive, females. Although it is possible to identify a critical region within the subthalamus whose destruction eliminates male sexual behaviour, sexually-relevant neuronal cell bodies appear to be distributed throughout the lateral hypothalamic/incertal/tegmental continuum.
在雄性大鼠中，使用鹅膏蕈氨酸和N-甲基-D-天冬氨酸来破坏一个从前到后的连续区域内的神经元胞体，该区域包括尾侧未定带和外侧被盖区。一些损伤实际上消除了雄性性行为——这种效应与下丘脑外侧区和未定带的损伤关系最为密切。许多与正常活跃的雌性大鼠交配至射精的损伤雄性大鼠，与处于接受期但相对不活跃的雌性大鼠几乎没有或完全没有交配行为。虽然有可能在下丘脑底区内确定一个关键区域，其破坏会消除雄性性行为，但与性相关的神经元细胞体似乎分布于整个下丘脑外侧/未定带/被盖区的连续区域。
