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肾移植受者肌间隔综合征:一种未得到充分认识的术后并发症。

Renal allograft compartment syndrome: an underappreciated postoperative complication.

作者信息

Ball Chad G, Kirkpatrick Andrew W, Yilmaz Serdar, Monroy Mauricio, Nicolaou Savvas, Salazar Anastasio

机构信息

Department of Surgery, Foothills Medical Centre, 1403 29 St. N.W., Calgary, Alberta, Canada T2N 2T9.

出版信息

Am J Surg. 2006 May;191(5):619-24. doi: 10.1016/j.amjsurg.2006.02.013.

Abstract

PURPOSE

Renal allograft compartment syndrome (RACS) is early graft dysfunction secondary to retroperitoneal hypertension and resultant ischemia. Our purpose was to identify the incidence, therapies and outcomes of patients with RACS.

METHODS

All patients who underwent a renal transplant between 2000 and 2005 were reviewed. Patients with signs of acute allograft dysfunction were identified. RACS was diagnosed via visual allograft hypoperfusion and/or with preoperative Doppler ultrasound.

RESULTS

Among 458 patients, 11 (2%) were diagnosed with RACS. Characteristics between patient groups were similar. Five (45%) patients displayed adequate initial allograft function after transplantation. Doppler ultrasound was diagnostic. Six (55%) patients displayed poor initial allograft function and were classified as early presenters of RACS. Allograft function improved dramatically upon decompression.

CONCLUSIONS

Clinicians must remain aware of RACS as a potential diagnosis when patients display rapid deterioration in kidney performance after good initial allograft function. Doppler ultrasound is useful in diagnosing late presenters.

摘要

目的

肾移植受者隔室综合征(RACS)是继发于腹膜后高压及由此导致的缺血的早期移植肾功能障碍。我们的目的是确定RACS患者的发病率、治疗方法及预后。

方法

回顾了2000年至2005年间接受肾移植的所有患者。确定有急性移植肾功能障碍体征的患者。通过肉眼观察移植肾灌注不足和/或术前多普勒超声诊断RACS。

结果

458例患者中,11例(2%)被诊断为RACS。患者组间特征相似。5例(45%)患者移植后初期移植肾功能良好。多普勒超声具有诊断价值。6例(55%)患者移植后初期移植肾功能差,被归类为RACS早期表现者。减压后移植肾功能显著改善。

结论

当患者在移植肾初期功能良好后肾功能迅速恶化时,临床医生必须意识到RACS这一潜在诊断。多普勒超声对晚期表现者的诊断有用。

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