Xu Q M
PLA General Hospital, Beijing.
Zhonghua Zhong Liu Za Zhi. 1991 May;13(3):204-6.
Twelve cases of multiple primary bronchogenic carcinoma out of 745 operated and pathologically confirmed ones are reported, with an incidence of 1.6%. There were 1 female and 11 males. The ages ranged 36-72 with a mean value of 61.9. Eleven had double and 1, had triple lesions. The pathologic relationship was squamous-squamous carcinoma in 4 cases, squamous-small cell carcinoma in 3, squamous-adenocarcinoma in 1, undifferentiated-giant cell carcinoma in 1, bronchiolo-alveolar bronchiolo-alveolar carcinoma in 1 and adeno-adenocarcinoma in 1. The triple primary lesions were all adenocarcinoma. The cause of increase in incidence, clinical manifestations, diagnosis, differential diagnosis and surgical treatment are discussed.
报告了745例接受手术并经病理确诊的病例中的12例多原发性支气管癌,发病率为1.6%。其中女性1例,男性11例。年龄范围为36 - 72岁,平均年龄为61.9岁。11例为双发病变,1例为三发病变。病理关系为4例鳞状-鳞状癌,3例鳞状-小细胞癌,1例鳞状-腺癌,1例未分化-巨细胞癌,1例细支气管肺泡-细支气管肺泡癌,1例腺-腺癌。三原发性病变均为腺癌。文中讨论了发病率增加的原因、临床表现、诊断、鉴别诊断及手术治疗。