Gotoh M, Griffin C, Hruban Z
Virchows Arch B Cell Pathol. 1975;17(4):279-94. doi: 10.1007/BF02912855.
Feeding of acetylsalicylic acid (ASA), clofibrate and dimethrin induces formation of matrical plates in heptaic microbodies. Administration of sodium citrate prevents formation of matrical plates in rats fed ASA, but not in rats treated with clofibrate or dimethrin. Propionate has a similar effect on rats fed ASA but not those fed clofibrate. Feeding of aminotriazole prevents formation of matrical plates in rats fed ASA without inhibiting the proliferation of microbodies. Sodium citrate and aminotriazole and feeding decrease also the activity of hepatic catalase in rats fed ASA.
给大鼠喂食乙酰水杨酸(ASA)、氯贝丁酯和苄氯菊酯会诱导肝微体中基质板的形成。给予柠檬酸钠可防止喂食ASA的大鼠形成基质板,但对用氯贝丁酯或苄氯菊酯处理的大鼠无效。丙酸盐对喂食ASA的大鼠有类似作用,但对喂食氯贝丁酯的大鼠无效。喂食氨基三唑可防止喂食ASA的大鼠形成基质板,而不抑制微体的增殖。柠檬酸钠、氨基三唑和喂食也会降低喂食ASA的大鼠肝脏过氧化氢酶的活性。