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柠檬酸盐和氨基三唑对肝微体中诱导生成的基质板的影响。

Effect of citrate and aminotriazole on matrical plates induced in hepatic microbodies.

作者信息

Gotoh M, Griffin C, Hruban Z

出版信息

Virchows Arch B Cell Pathol. 1975;17(4):279-94. doi: 10.1007/BF02912855.

DOI:10.1007/BF02912855
PMID:166481
Abstract

Feeding of acetylsalicylic acid (ASA), clofibrate and dimethrin induces formation of matrical plates in heptaic microbodies. Administration of sodium citrate prevents formation of matrical plates in rats fed ASA, but not in rats treated with clofibrate or dimethrin. Propionate has a similar effect on rats fed ASA but not those fed clofibrate. Feeding of aminotriazole prevents formation of matrical plates in rats fed ASA without inhibiting the proliferation of microbodies. Sodium citrate and aminotriazole and feeding decrease also the activity of hepatic catalase in rats fed ASA.

摘要

给大鼠喂食乙酰水杨酸(ASA)、氯贝丁酯和苄氯菊酯会诱导肝微体中基质板的形成。给予柠檬酸钠可防止喂食ASA的大鼠形成基质板,但对用氯贝丁酯或苄氯菊酯处理的大鼠无效。丙酸盐对喂食ASA的大鼠有类似作用,但对喂食氯贝丁酯的大鼠无效。喂食氨基三唑可防止喂食ASA的大鼠形成基质板,而不抑制微体的增殖。柠檬酸钠、氨基三唑和喂食也会降低喂食ASA的大鼠肝脏过氧化氢酶的活性。

相似文献

1
Effect of citrate and aminotriazole on matrical plates induced in hepatic microbodies.柠檬酸盐和氨基三唑对肝微体中诱导生成的基质板的影响。
Virchows Arch B Cell Pathol. 1975;17(4):279-94. doi: 10.1007/BF02912855.
2
Structure of hepatic microbodies in rats treated with acetylsalicylic acid, clofibrate, and dimethrin.用乙酰水杨酸、氯贝丁酯和苄氯菊酯处理的大鼠肝脏微体的结构
Lab Invest. 1974 Jan;30(1):64-75.
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Matrical inclusions induced by clofibrate in hepatic microbodies of rats fed 2-acetylaminofluorene.氯贝丁酯在喂食2-乙酰氨基芴的大鼠肝脏微体中诱导产生的基质包涵体。
J Natl Cancer Inst. 1975 Feb;54(2):519-23.
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Matrical inclusions of peroxisomes induced by clofibrate in preneoplastic hepatocytes of rats fed 3'-methyl-4-dimethyl-aminoazobenzene.在喂食3'-甲基-4-二甲基氨基偶氮苯的大鼠的癌前肝细胞中,氯贝丁酯诱导的过氧化物酶体基质内含物。
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Response of microbodies in Morris hepatoma 9618A to clofibrate.莫里斯肝癌9618A中微体对氯贝丁酯的反应。
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The effects of clofibrate and 3-amino-1,2,4-triazole on liver catalase and lipid metabolism in mice.氯贝丁酯和3-氨基-1,2,4-三唑对小鼠肝脏过氧化氢酶及脂质代谢的影响
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Effect of clofibrate application on morphology and enzyme content of liver peroxisomes.氯贝丁酯应用对肝脏过氧化物酶体形态和酶含量的影响。
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Differential increase of hepatic peroxisomal, mitochondrial and microsomal carnitine acyltransferases in clofibrate-fed rats.氯贝丁酯喂养的大鼠肝脏过氧化物酶体、线粒体和微粒体肉碱酰基转移酶的差异增加。
Biochem Pharmacol. 1977 Sep 15;26(18):1697-702. doi: 10.1016/0006-2952(77)90147-2.
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On the synthesis and degradation of the multiple forms of catalase in mouse liver: effects of aminotriazole and p-chlorophenoxyisobutric acid ethyl ester.关于小鼠肝脏中过氧化氢酶多种形式的合成与降解:氨基三唑和对氯苯氧基异丁酸乙酯的作用
Arch Biochem Biophys. 1978 Apr 30;187(2):431-40. doi: 10.1016/0003-9861(78)90054-1.

引用本文的文献

1
Serial section analysis of mouse hepatic peroxisomes.小鼠肝脏过氧化物酶体的连续切片分析
Anat Embryol (Berl). 1985;172(1):21-32. doi: 10.1007/BF00318940.
2
Unusual responses of rat hepatic and renal peroxisomes to RMI 14, 514, a new hypolipidemic agent.大鼠肝脏和肾脏过氧化物酶体对新型降血脂药物RMI 14,514的异常反应。
J Cell Biol. 1978 Sep;78(3):810-22. doi: 10.1083/jcb.78.3.810.