Alvarez Luis, Alcaraz María, Pérez-Higueras Antonio, Granizo Juan J, de Miguel Ignacio, Rossi Roberto E, Quiñones Diana
Department of Orthopaedics,Fundación Jiménez Díaz, Madrid, Spain.
Spine (Phila Pa 1976). 2006 May 1;31(10):1113-8. doi: 10.1097/01.brs.0000216487.97965.38.
Prospective, double-cohort study.
To evaluate conservative and percutaneous vertebroplasty (PV) management of osteoporotic vertebral fractures.
PV is an elective alternative to conservative management for the treatment of a painful osteoporotic vertebral fracture.
We performed a prospective study consisting of 101 consecutive patients who underwent PV and 27 patients who refused PV treatment and were managed conservatively. We used a data evaluation and outcomes system that was developed to evaluate the outcomes of surgical intervention.
Patients that elected for PV as a treatment of their fractures had significantly more pain and functional impairment before the procedure than the patients of the conservative group (P < 0.001). The pain, functional, and general health scores of the PV group were improved from the preoperative mean values (P < 0.001) in all postoperative periods. Compared with the conservative treatment group, there was a significant difference at month 3. However, no statistical differences on function were observed between these groups at 6 months and 1 year posttreatment.
PV demonstrated a rapid and significant relief of pain and improved the quality of life. PV election for treatment of painful osteoporotic vertebral fracture after 6 weeks of conservative treatment was based on pain and functional impairment.
前瞻性双队列研究。
评估骨质疏松性椎体骨折的保守治疗和经皮椎体成形术（PV）治疗效果。
PV是治疗疼痛性骨质疏松性椎体骨折的一种选择性替代保守治疗方法。
我们进行了一项前瞻性研究，纳入101例连续接受PV治疗的患者和27例拒绝PV治疗而接受保守治疗的患者。我们使用了一个为评估手术干预结果而开发的数据评估和结果系统。
选择PV治疗骨折的患者在手术前的疼痛和功能障碍明显比保守治疗组患者更严重（P < 0.001）。PV组的疼痛、功能和总体健康评分在术后各阶段均较术前平均值有所改善（P < 0.001）。与保守治疗组相比，在术后3个月时有显著差异。然而，在治疗后6个月和1年时，这些组之间在功能方面未观察到统计学差异。
PV显示出能迅速且显著地缓解疼痛并改善生活质量。保守治疗6周后选择PV治疗疼痛性骨质疏松性椎体骨折是基于疼痛和功能障碍情况。
