Pedersen A
Dental Department, University Hospital-Rigshospitalet, Copenhagen, Denmark.
Med Hypotheses. 1991 Nov;36(3):206-10. doi: 10.1016/0306-9877(91)90132-i.
The etiology of recurrent oral aphthous ulcers (RAU) remains unsolved. The present article relates previous immunopathologic findings in RAU to a possible viral etiopathogenesis with special reference to the herpes virus family. It is concluded that RAU might be of viral etiology, and it is furthermore speculated that the aphthous ulcers may be the clinical manifestation of 'latent' varicella-zoster virus reactivation (reinfection).
复发性口腔溃疡（RAU）的病因尚未明确。本文将RAU先前的免疫病理学发现与可能的病毒病因联系起来，特别提及疱疹病毒家族。结论认为RAU可能由病毒引起，并且进一步推测口腔溃疡可能是“潜伏”的水痘-带状疱疹病毒再激活（再感染）的临床表现。
