Doyle Frank, McGee Hannah M, De La Harpe Davida, Shelley Emer, Conroy Ronán
Department of Psychology, Royal College of Surgeons in Ireland, 120 St Stephen's Green, Dublin 2, Ireland.
J Psychosom Res. 2006 May;60(5):461-7. doi: 10.1016/j.jpsychores.2005.09.004.
The objective of this study was to investigate the use of short-form depression scales in assessing 1-year mortality risk in a national sample of patients with acute coronary syndrome (ACS).
Patients with ACS (N=598) completed either the Hospital Anxiety and Depression Scale depression subscale (HADS-D) or the Beck Depression Inventory-Fast Scale (BDI-FS). Their mortality status was assessed at 1 year.
Cox proportional hazards modeling showed that patients depressed at baseline (combining HADS-D and BDI-FS depressed cases) were more likely to die within 1 year [hazard ratio (HR)=2.8, 95% CI=1.4-5.7, P=.005], even when controlling for major medical and demographic variables (HR=4.1, 95% CI=1.6-10.3, P=.003). Scoring above the threshold on the HADS-D predicted mortality (HR=4.2, 95% CI=1.8-10.0, P=.001), but scoring above the threshold on the BDI-FS did not (HR=1.8, 95% CI=0.6-5.6, P=.291).
The HADS-D predicted increased risk of 1-year mortality in patients with ACS.
本研究的目的是调查在全国急性冠状动脉综合征（ACS）患者样本中，使用简短抑郁量表评估1年死亡风险的情况。
ACS患者（N = 598）完成了医院焦虑抑郁量表抑郁分量表（HADS-D）或贝克抑郁量表快速版（BDI-FS）。在1年时评估他们的死亡状态。
Cox比例风险模型显示，基线时抑郁的患者（合并HADS-D和BDI-FS抑郁病例）在1年内死亡的可能性更大[风险比（HR）= 2.8，95%置信区间（CI）= 1.4 - 5.7，P = 0.005]，即使在控制主要医疗和人口统计学变量后（HR = 4.1，95% CI = 1.6 - 10.3，P = 0.003）。HADS-D得分高于阈值可预测死亡率（HR = 4.2，95% CI = 1.8 - 10.0，P = 0.001），但BDI-FS得分高于阈值则不能（HR = 1.8，95% CI = 0.6 - 5.6，P = 0.291）。
HADS-D可预测ACS患者1年死亡风险增加。
