Siddhu A, Sud S, Bijlani R L, Karmarkar M G, Nayar U
Department of Physiology, All India Institute of Medical Sciences, New Delhi.
Indian J Physiol Pharmacol. 1991 Apr;35(2):99-105.
The present study was designed to examine the effect of corn oil (Co) on postprandial glycaemia and insulinaemia when ingested with glucose (G), casein (Cs), cellulose (Cl) and pectin (P) in various combinations. The study was conducted on six healthy male volunteers, on each of whom six meal tolerance tests were performed. The meals were isocaloric and consisted of G; G and Co; G, Co and Cs; G, Co and P; G, Co, Cs and P; and G, Co, Cs and Cl. The meals were administered after an overnight fast. In addition to a fasting blood sample, blood was collected 0.5, 1.0, 1.5 and 2.0 h after ingestion for measurement of serum glucose and insulin levels. The glycaemic response to GCo was comparable to that to G, but the insulinaemic response was significantly lower. The glycaemic response to GCoCs was significantly lower than that to G but the insulinaemic response to both was comparable. The cellulose containing meal GCoCsCl showed a further reduction in the glycaemic response but not in the insulinaemic response. The pectin containing meals GCoP and GCoCsP gave the lowest glycaemic and insulinaemic responses, the responses to the latter being lower. Corn oil by itself has only a modest effect on the postprandial metabolic response to glucose. Addition of protein and fibre, specially pectin, leads to significant attenuation of glycaemic and insulinaemic responses.
本研究旨在检测玉米油（Co）与葡萄糖（G）、酪蛋白（Cs）、纤维素（Cl）和果胶（P）以不同组合摄入时对餐后血糖和胰岛素血症的影响。该研究针对六名健康男性志愿者开展，对每人进行了六次进餐耐量试验。餐食热量相同，分别为：G；G和Co；G、Co和Cs；G、Co和P；G、Co、Cs和P；以及G、Co、Cs和Cl。餐食在禁食过夜后给予。除了采集空腹血样外，在摄入后0.5、1.0、1.5和2.0小时采集血样，以测量血清葡萄糖和胰岛素水平。对GCo的血糖反应与对G的相当，但胰岛素反应显著较低。对GCoCs的血糖反应显著低于对G的，但两者的胰岛素反应相当。含纤维素的餐食GCoCsCl的血糖反应进一步降低，但胰岛素反应未降低。含果胶的餐食GCoP和GCoCsP的血糖和胰岛素反应最低，对后者的反应更低。玉米油本身对餐后葡萄糖代谢反应的影响较小。添加蛋白质和纤维，特别是果胶，会导致血糖和胰岛素反应显著减弱。
