Moum B, Aukrust P, Bjørneklett A, Frøland S S, Farstad I N, Holter E
Medisinsk avdeling A, Kaptein W. Wilhelmsen og frues bakteriologiske institutt, Rikshospitalet, Oslo.
Tidsskr Nor Laegeforen. 1991 Nov 20;111(28):3388-91.
Cytomegalovirus infections in immunocompromised patients may cause serious illness, particularly in patients with HIV-disease and in transplant recipients. There is an increasing number of reports of cytomegalovirus infections involving the alimentary tract, especially colitis. Diagnosis of cytomegalovirus disease is at present based on specific histological findings. Antibody findings can be difficult to interpret. The slow growth of cytomegalovirus in cultures makes this method less useful in the acute setting of diagnosis. It is important to recognize cytomegalovirus colitis as a differential diagnosis to idiopathic inflammatory bowel disease. In fulminant disease, colectomy should be considered in addition to antiviral treatment.
免疫功能低下患者的巨细胞病毒感染可能导致严重疾病，尤其是在患有HIV疾病的患者和移植受者中。涉及消化道尤其是结肠炎的巨细胞病毒感染报告越来越多。目前巨细胞病毒疾病的诊断基于特定的组织学发现。抗体检测结果可能难以解读。巨细胞病毒在培养物中生长缓慢，这使得该方法在急性诊断中用处较小。将巨细胞病毒性结肠炎作为特发性炎症性肠病的鉴别诊断很重要。在暴发性疾病中，除抗病毒治疗外，还应考虑行结肠切除术。
