Fowden A L, Mundy L, Ousey J C, McGladdery A, Silver M
Physiological Laboratory, Cambridge, U.K.
J Reprod Fertil Suppl. 1991;44:537-42.
Glycogen and glucose 6-phosphatase levels were measured in a variety of tissues from fetal, newborn and adult pregnant mares. Hepatic and renal glucose 6-phosphatase activities increased with increasing gestational age and rose further in the 24 h after birth to values similar to those observed in maternal tissues. The glycogen content of fetal liver and skeletal muscle also increased in late gestation, whereas that of fetal lung and cardiac muscle decreased toward term. No significant change in renal glycogen content with fetal age was observed. The values of hepatic glycogen and glucose 6-phosphatase found in the fetal foal near term were less than those observed previously in fetal sheep and pigs at a similar stage of gestation. These observations suggest that, in late gestation, the fetal foal has a limited glucogenic capacity compared with other domestic species and may have difficulty maintaining an adequate glucose supply during adverse conditions.
在胎儿、新生和成年妊娠母马的多种组织中测量了糖原和葡萄糖6磷酸酶水平。肝脏和肾脏的葡萄糖6磷酸酶活性随着胎龄增加而升高，并在出生后24小时进一步上升至与母体组织中观察到的值相似。胎儿肝脏和骨骼肌的糖原含量在妊娠后期也增加，而胎儿肺和心肌的糖原含量在足月时下降。未观察到肾脏糖原含量随胎龄有显著变化。接近足月的胎儿小马肝脏糖原和葡萄糖6磷酸酶的值低于先前在类似妊娠阶段的胎儿绵羊和猪中观察到的值。这些观察结果表明，在妊娠后期，与其他家养物种相比，胎儿小马的糖异生能力有限，在不利条件下可能难以维持充足的葡萄糖供应。
