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[脑电图频谱窄频带对证明地西泮对边缘性精神障碍患者疗效的意义]

[Significance of narrow frequency bands of the EEG spectrum for demonstrating the effect of diazepam in patients with borderline mental disorders].

作者信息

Bochkarev V K, Serebriakova T V

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(10):73-7.

PMID:1665660
Abstract

A study was made of the effect of the single test dose of diazepam (10 mg, i. m.) and continuous drug therapy on the narrow spectral bands of the EEG in the range of 0.4-30.0 Hz. A relationship was demonstrated between the pattern of EEG changes and individual intensity in patients of the clinical manifestations of activation, tranquilization and sedation as well as the total efficacy of continuous therapy, disease standing and previous treatment. The frequencies of alpha-rhythm were found to be more informative for the reflection of the clinico-electrophysiological correlations established.

摘要

研究了单次试验剂量的地西泮(10毫克,肌肉注射)和持续药物治疗对脑电图在0.4 - 30.0赫兹范围内窄谱带的影响。结果表明,脑电图变化模式与患者激活、镇静和安定临床表现的个体强度之间存在关联,以及持续治疗的总疗效、疾病状况和先前治疗情况。发现α波节律频率对于反映所建立的临床 - 电生理相关性更具信息价值。

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Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(10):73-7.
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[Changes in the narrow-band components of the EEG spectrum under the action of nootropic drugs].[益智药物作用下脑电图频谱窄带成分的变化]
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On the central effects of a new partial benzodiazepine agonist Ro 16-6028 in man: pharmaco-EEG and psychometric studies.新型部分苯二氮䓬激动剂Ro 16-6028对人体的中枢作用:药物脑电图和心理测量学研究。
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Effects of diazepam and zolpidem on EEG beta frequencies are behavior-specific in rats.地西泮和唑吡坦对大鼠脑电图β频率的影响具有行为特异性。
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