Asensio Lahoz L A, Sandoval González F, Abaitua Bilbao J, Palazuelos C M, del Valle Schaan J I, García Montesinos M, de La Torriente Oria J I, García de Tuñon A, Lanzas Prieto J M
Hospital Universitario Marqués de Valdecilla, Santander, España.
Arch Esp Urol. 1991 Oct;44(8):989-92.
We reviewed the records of patients with genitourinary tumors that had been diagnosed and treated at the Section of Pediatric Surgery of Marqués de Valdecilla Hospital from 1974 to 1990. There were 14 such tumors. Of these, 12 (85.7%) were Wilm's tumor. This tumor type is the subject of the present study. Regarding its clinical features, 33.3% of the cases consulted for hematuria and an abdominal mass was the most common finding in the course of the disease (83%). We underscore the usefulness of CT and ultrasound in making the diagnosis. In the cases where these noninvasive imaging techniques were used, their efficacy rate was 100%. Together with IVP, these constitute the fundamental diagnostic tools. With regard to treatment, radical nephrectomy was performed in all cases and combined with radio and chemotherapy according to protocol. Pathological examination confirmed the diagnosis of Wilms' tumor in all the cases. Following the NWTS classification, there were 2 stage I,5 stage II, 2 stage III and 3 stage IV. Apart from tumor stage, the histological features significantly influenced the diagnosis. The survival rates for those with favourable or unfavourable histologic features were 70% and 36%, respectively.
我们回顾了1974年至1990年在瓦尔迪西利亚侯爵医院小儿外科确诊并接受治疗的泌尿生殖系统肿瘤患者的病历。共有14例此类肿瘤。其中，12例（85.7%）为肾母细胞瘤。本研究以这种肿瘤类型为主题。关于其临床特征，33.3%的病例因血尿就诊，腹部肿块是疾病过程中最常见的表现（83%）。我们强调CT和超声在诊断中的作用。在使用这些非侵入性成像技术的病例中，其有效率为100%。与静脉肾盂造影一起，这些构成了基本的诊断工具。关于治疗，所有病例均进行了根治性肾切除术，并根据方案联合放疗和化疗。病理检查在所有病例中均确诊为肾母细胞瘤。按照NWTS分类，有2例I期、5例II期、2例III期和3例IV期。除肿瘤分期外，组织学特征对诊断有显著影响。组织学特征良好或不良者的生存率分别为70%和36%。
