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[大脑微循环床中的血细胞比容]

[The hematocrit in the microcirculatory bed of the brain].

作者信息

Varazashvili M N, Mchedlishvili G I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1991 Jun;77(6):12-9.

PMID:1665808
Abstract

Concentration of erythrocytes (hematocrit) was assessed in blood samples taken from small veins of the brain and the hindlimbs of rabbits. Its values were regularly found to be higher by 20% in cerebral vessels than in the hindlimbs. These results corroborate our previous conclusion about preferential distribution of erythrocytes along the arterial ramifications to the brain where the metabolic rate and the blood flow are higher than in other parts of the body. The hematocrit in capillaries of the cerebral cortex was found to be higher than in the veins draining blood from its networks. During ischemia in the cerebral hemispheres the erythrocyte concentration regularly decreased both in the cortex capillaries and in the veins. These changes were independent of the systemic hematocrit, which remained unchanged under these conditions.

摘要

从兔脑和后肢的小静脉采集血样,评估红细胞浓度(血细胞比容)。结果发现,脑血管中的红细胞浓度值通常比后肢高20%。这些结果证实了我们之前的结论,即红细胞优先沿动脉分支分布到大脑,因为大脑的代谢率和血流量高于身体其他部位。发现大脑皮质毛细血管中的血细胞比容高于从其网络引流血液的静脉中的血细胞比容。在大脑半球缺血期间,皮质毛细血管和静脉中的红细胞浓度均有规律地降低。这些变化与全身血细胞比容无关,在这些条件下全身血细胞比容保持不变。

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