Owczarek H, Lewczuk E
Department of Medical Analytics, Medical Academy Wroclaw, Poland.
Pol J Occup Med Environ Health. 1991;4(2):127-33.
Type-III-procollagen peptide (P-III-P) concentration and angiotensin-converting-enzyme (ACE) activity were measured in the serum of asbestos workers. The subjects were classified into four groups (A, B, C, D) according to the duration of exposure (in years). A gradual increase of ACE activity in group B and P-III-P concentration in group C was found. The increase in ACE activity can be regarded as the response to the progressing inflammatory state, and the increase in P-III-P concentration may be related to the fibrosis of the lung tissue.
在石棉工人的血清中测量了III型前胶原肽（P-III-P）浓度和血管紧张素转换酶（ACE）活性。根据接触年限（以年为单位）将受试者分为四组（A、B、C、D）。发现B组中ACE活性逐渐增加，C组中P-III-P浓度逐渐增加。ACE活性的增加可被视为对炎症状态进展的反应，而P-III-P浓度的增加可能与肺组织纤维化有关。
