Lycke E
Department of Clinical Virology, University of Göteborg, Sweden.
Scand J Infect Dis Suppl. 1991;80:7-14.
This review discusses some of the many virus- and host-specified biological characteristics with an impact on the pathogenesis and the natural course of the genital herpesvirus infection. Thus the influence of some virus genetic factors is evaluated, the present state of what is known about conditions affecting establishment and reactivation of latency is related and, finally, some aspects on the importance for the pathogenesis of some immune reactions and the immunological surveillance of the reactivated infection are commented.
本综述讨论了许多病毒和宿主特异性生物学特征中的一些,这些特征对生殖器疱疹病毒感染的发病机制和自然病程有影响。因此,评估了一些病毒遗传因素的影响,阐述了影响潜伏期建立和再激活的已知情况的现状,最后,对一些免疫反应对发病机制的重要性以及对再激活感染的免疫监测的一些方面进行了评论。