Sollertinskaia T N, Obidova M
Fiziol Zh SSSR Im I M Sechenova. 1991 Oct;77(10):10-9.
The effect of opioid neuropeptides was found to be more obvious in functional pathology of the higher nervous activity in hedgehogs. Met-enkephalin exerted a more obvious and longer-lasting effect on complicated forms of nervous activity, particularly inherent those. Naloxone abolished the met-enkephalin effect. The comparative effect of different opioid neuropeptides on inherent and acquired forms of nervous activity in mammals, the correlation between structural distribution of the neuropeptides and their functional properties, are discussed.
研究发现,阿片类神经肽在刺猬高级神经活动的功能病理学中作用更为明显。甲硫氨酸脑啡肽对复杂形式的神经活动,尤其是那些固有神经活动,具有更明显且持久的作用。纳洛酮可消除甲硫氨酸脑啡肽的作用。文中讨论了不同阿片类神经肽对哺乳动物固有和习得性神经活动形式的比较作用,以及神经肽的结构分布与其功能特性之间的相关性。