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促肾上腺皮质激素与β-内啡肽在调节刺猬条件反射活动中作用的比较研究

[A comparative study of the role of ACTH and beta-endorphin in regulating the conditioned-reflex activity of hedgehogs].

作者信息

Sollertinskaia T N

出版信息

Fiziol Zh Im I M Sechenova. 1995 Dec;81(12):20-30.

PMID:8754024
Abstract

The ACTH was shown to facilitate learning and to enhance the memory processes in hedgehogs. Administration of beta-endorphin enhanced the latency of conditioning, exert an analgetic effect, reduced the motor and intersignal activities, as well as eliminated the inhibitory effects of the limbic cortex stimulation. Different influences of the ACTH and beta-endorphin upon the higher nervous activity as well as possible mechanisms of these effects, are discussed.

摘要

促肾上腺皮质激素已被证明可促进刺猬的学习并增强其记忆过程。β-内啡肽的施用延长了条件反射的潜伏期,发挥了镇痛作用,降低了运动和信号间活动,还消除了边缘皮质刺激的抑制作用。文中讨论了促肾上腺皮质激素和β-内啡肽对高级神经活动的不同影响以及这些影响可能的机制。

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