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美国和英国的疾病与劣势。

Disease and disadvantage in the United States and in England.

作者信息

Banks James, Marmot Michael, Oldfield Zoe, Smith James P

机构信息

University College London and Institute for Fiscal Studies, London, England.

出版信息

JAMA. 2006 May 3;295(17):2037-45. doi: 10.1001/jama.295.17.2037.

DOI:10.1001/jama.295.17.2037
PMID:16670412
Abstract

CONTEXT

The United States spends considerably more money on health care than the United Kingdom, but whether that translates to better health outcomes is unknown.

OBJECTIVE

To assess the relative heath status of older individuals in England and the United States, especially how their health status varies by important indicators of socioeconomic position.

DESIGN, SETTING, AND PARTICIPANTS: We analyzed representative samples of residents aged 55 to 64 years from both countries using 2002 data from the US Health and Retirement Survey (n = 4386) and the English Longitudinal Study of Aging (n = 3681), which were designed to have directly comparable measures of health, income, and education. This analysis is supplemented by samples of those aged 40 to 70 years from the 1999-2002 waves of National Health and Nutrition Examination Survey (n = 2097) and the 2003 wave of the Health Survey for England (n = 5526). These surveys contain extensive and comparable biological disease markers on respondents, which are used to determine whether differential propensities to report illness can explain these health differences. To ensure that health differences are not solely due to health issues in the black or Latino populations in the United States, the analysis is limited to non-Hispanic whites in both countries.

MAIN OUTCOME MEASURE

Self-reported prevalence rates of several chronic diseases related to diabetes and heart disease, adjusted for age and health behavior risk factors, were compared between the 2 countries and across education and income classes within each country.

RESULTS

The US population in late middle age is less healthy than the equivalent British population for diabetes, hypertension, heart disease, myocardial infarction, stroke, lung disease, and cancer. Within each country, there exists a pronounced negative socioeconomic status (SES) gradient with self-reported disease so that health disparities are largest at the bottom of the education or income variants of the SES hierarchy. This conclusion is generally robust to control for a standard set of behavioral risk factors, including smoking, overweight, obesity, and alcohol drinking, which explain very little of these health differences. These differences between countries or across SES groups within each country are not due to biases in self-reported disease because biological markers of disease exhibit exactly the same patterns. To illustrate, among those aged 55 to 64 years, diabetes prevalence is twice as high in the United States and only one fifth of this difference can be explained by a common set of risk factors. Similarly, among middle-aged adults, mean levels of C-reactive protein are 20% higher in the United States compared with England and mean high-density lipoprotein cholesterol levels are 14% lower. These differences are not solely driven by the bottom of the SES distribution. In many diseases, the top of the SES distribution is less healthy in the United States as well.

CONCLUSION

Based on self-reported illnesses and biological markers of disease, US residents are much less healthy than their English counterparts and these differences exist at all points of the SES distribution.

摘要

背景

美国在医疗保健方面的支出比英国多得多,但这是否能转化为更好的健康结果尚不清楚。

目的

评估英格兰和美国老年人的相对健康状况,特别是他们的健康状况如何因社会经济地位的重要指标而有所不同。

设计、地点和参与者:我们使用来自美国健康与退休调查(n = 4386)和英国老龄化纵向研究(n = 3681)的2002年数据,分析了两国55至64岁居民的代表性样本,这些数据旨在对健康、收入和教育进行直接可比的测量。1999 - 2002年国家健康与营养检查调查(n = 2097)中40至70岁人群的样本以及2003年英格兰健康调查(n = 5526)对这一分析起到了补充作用。这些调查包含了受访者广泛且可比的生物疾病标志物,用于确定报告疾病的不同倾向是否能够解释这些健康差异。为确保健康差异并非仅仅源于美国黑人或拉丁裔人群的健康问题,分析仅限于两国的非西班牙裔白人。

主要结局指标

比较了两国之间以及每个国家内不同教育和收入阶层中,几种与糖尿病和心脏病相关的慢性病经年龄和健康行为风险因素调整后的自我报告患病率。

结果

美国接近中年的人群在糖尿病、高血压、心脏病、心肌梗死、中风、肺病和癌症方面的健康状况不如英国同龄人。在每个国家内部,自我报告疾病与社会经济地位(SES)之间存在明显的负相关梯度,因此健康差距在SES等级制度中教育或收入较低的人群中最为显著。这一结论在控制了包括吸烟、超重、肥胖和饮酒在内的一组标准行为风险因素后通常依然成立,而这些因素对这些健康差异的解释作用很小。国家之间或每个国家内不同SES群体之间的这些差异并非由于自我报告疾病的偏差,因为疾病的生物标志物呈现出完全相同的模式。举例来说,在55至64岁的人群中,美国的糖尿病患病率是英国的两倍,而这一差异中只有五分之一可以由一组常见风险因素来解释。同样,在中年成年人中,美国的C反应蛋白平均水平比英国高20%,高密度脂蛋白胆固醇平均水平比英国低14%。这些差异并非仅仅由SES分布的底层人群所驱动。在许多疾病中,美国SES分布顶层人群的健康状况也较差。

结论

基于自我报告的疾病情况和疾病的生物标志物,美国居民的健康状况远不如英国居民,并且这些差异在SES分布的各个层面都存在。

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