Ali Javadi Mohammad, Sharifi Ali, Hashemian Seyed Javad, Yazdani Shahin, Parvizi Gilda, Kanavi Mozhgan Rezaei
Department of Ophthalmology, Shaeed Beheshti University of Medical Science, Ophthalmic Research Center, Tehran, Iran.
Cornea. 2006 May;25(4):479-81. doi: 10.1097/01.ico.0000178727.49811.c7.
The clinical and pathologic characteristics and the surgical treatment of 2 patients with intrastromal corneal epithelial cysts are described.
This interventional case report presents 2 young patients with decreased vision and cosmetic impairment caused by intracorneal epithelial cysts. The first patient had history of strabismus surgery, and the second patient had undergone corneal laceration repair. The cysts had enlarged gradually and dissected into the cornea, threatening the visual axis. Both patients were treated with drainage of cyst contents, chemical cytodestruction with 96% ethanol for 1 minute in a closed system, followed by cyst wall excision.
Corneal clarity and appearance improved significantly after surgery. In the first patient, best-corrected visual acuity was 20/20 before the operation and remained stable. In the second patient, best-corrected visual acuity improved from 20/400 to 20/60 after the procedure. Histopathologic findings revealed that the cyst walls were composed of nonkeratinized stratified squamous epithelium. No recurrence was noted up to 8 and 3 months in the first and second patients, respectively. No complication occurred during the follow-up period.
Intracorneal epithelial cysts may be treated safely and effectively with a combination of drainage of cyst contents, irrigation with 96% ethanol, and cyst wall excision with good visual and cosmetic results.
描述2例角膜基质内上皮囊肿患者的临床和病理特征以及手术治疗情况。
本介入性病例报告介绍了2例因角膜内上皮囊肿导致视力下降和外观受损的年轻患者。首例患者有斜视手术史，第二例患者曾接受角膜裂伤修复术。囊肿逐渐增大并向角膜深层发展，威胁视轴。两名患者均接受了囊肿内容物引流、在封闭系统中用96%乙醇进行化学细胞破坏1分钟，随后切除囊肿壁的治疗。
术后角膜透明度和外观明显改善。首例患者术前最佳矫正视力为20/20，术后保持稳定。第二例患者术后最佳矫正视力从20/400提高到20/60。组织病理学检查结果显示囊肿壁由非角化复层鳞状上皮组成。首例和第二例患者分别随访8个月和3个月均未见复发。随访期间未发生并发症。
角膜内上皮囊肿采用囊肿内容物引流、96%乙醇冲洗及囊肿壁切除联合治疗可安全有效地进行，视觉和外观效果良好。
