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先天性角膜基质内囊肿的手术切除及蒸馏水溶解术

Surgical excision and distilled water lysis of a congenital corneal intrastromal cyst.

作者信息

Little Leanne M, See Craig W

机构信息

Cleveland Clinic, Cole Eye Institute, Cleveland, OH, USA.

出版信息

Am J Ophthalmol Case Rep. 2020 Aug 6;19:100864. doi: 10.1016/j.ajoc.2020.100864. eCollection 2020 Sep.

DOI:10.1016/j.ajoc.2020.100864
PMID:32875147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7452139/
Abstract

PURPOSE

To describe imaging findings and encourage the use of distilled water as an adjuvant osmolytic in the surgical management of corneal intrastromal cysts.

OBSERVATIONS

A five-year-old female with no history of ocular trauma presented with a visually significant corneal opacity of the left eye. She was diagnosed with a presumed corneal intrastromal cyst and underwent surgical excision with distilled water osmolysis of the cyst cavity.

CONCLUSIONS AND IMPORTANCE

Optical coherence tomography (OCT) can confirm diagnosis of intrastromal cysts. Presumed epithelial cell nests remain visible at post-operative month eight, with no evidence for cyst recurrence. The authors propose that OCT findings are pathognomonic for corneal intrastromal cysts and that cyst excision combined with distilled water osmolysis at the time of debridement may be beneficial in conserving tissue integrity.

摘要

目的

描述影像学表现,并鼓励在角膜基质内囊肿的手术治疗中使用蒸馏水作为辅助性渗透压溶解剂。

观察结果

一名无眼外伤史的5岁女性,左眼出现明显影响视力的角膜混浊。她被诊断为疑似角膜基质内囊肿,并接受了囊肿腔蒸馏水渗透压溶解的手术切除。

结论与意义

光学相干断层扫描(OCT)可确诊基质内囊肿。术后8个月仍可见疑似上皮细胞巢,无囊肿复发迹象。作者提出,OCT表现对角膜基质内囊肿具有诊断意义,在清创时囊肿切除联合蒸馏水渗透压溶解可能有助于保留组织完整性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aefd/7452139/3d41f53ddbf2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aefd/7452139/9fe7d88ef8b7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aefd/7452139/3d41f53ddbf2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aefd/7452139/9fe7d88ef8b7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aefd/7452139/3d41f53ddbf2/gr2.jpg

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本文引用的文献

1
Portable OCT-assisted surgical treatment of intracorneal pre-Descemet epithelial cyst: a case report.便携式光学相干断层扫描辅助下手术治疗角膜后弹力层前上皮囊肿:1例报告
BMC Ophthalmol. 2017 Aug 29;17(1):160. doi: 10.1186/s12886-017-0558-4.
2
Management of an intrastromal corneal epithelial cyst, from simple drainage to keratoplasty.基质内角膜上皮囊肿的治疗,从单纯引流到角膜移植术。
Oman J Ophthalmol. 2012 Sep;5(3):196-7. doi: 10.4103/0974-620X.106107.
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Traumatic epithelial inclusion cyst of the anterior corneal stroma.前角膜基质外伤性上皮植入性囊肿
Cornea. 2008 Apr;27(3):368-9. doi: 10.1097/ICO.0b013e31815d18ce.
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Bilateral congenital stromal cyst of the cornea.双侧先天性角膜基质囊肿
J AAPOS. 2007 Aug;11(4):400-1. doi: 10.1016/j.jaapos.2006.12.055. Epub 2007 Mar 13.
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Cornea. 2001 Mar;20(2):222-5. doi: 10.1097/00003226-200103000-00025.
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Cornea. 1999 Mar;18(2):233-6. doi: 10.1097/00003226-199903000-00015.
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Corneal cysts. A report of eight cases.
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